Mid-infrared (MIR) imaging and spectroscopic observations are presented for a well defined sample of eight closely interacting (CLO) pairs of spiral galaxies that have overlapping disks and show enhanced far-infrared (FIR) emission. The goal is to study the star formation distribution in CLO pairs, with special emphasis on the role of overlap starbursts. Observations were made with the Infrared Space Observatory (ISO) using the CAM and SWS instruments. The ISO~CAM maps, tracing the MIR emission of warm dust heated by young massive stars, are compared to new ground based H$alpha$ and R-band images. We identify three possible subgroups in the sample, classified according to the star formation morphology: (1) advanced mergers (Arp~157, Arp~244 and Arp~299), (2) severely disturbed systems (Arp~81 and Arp~278), and (3) less disturbed systems (Arp~276, KPG 347 and KPG 426). Localized starbursts are detected in the overlap regions in all five pairs of subgroups (1) and (2), suggesting that they are a common property in colliding systems. Except for Arp~244, the overlap starburst is usually fainter than the major nuclear starburst in CLO pairs. Star formation in less disturbed systems is often distributed throughout the disks of both galaxies with no overlap starburst detected in any of them. These systems also show less enhanced FIR emission, suggesting that they are in an earlier interaction stage than pairs of the other two subgroups where the direct disk collisions have probably not yet occurred.