We study conditions for the emergence of the preformed Cooper pairs in materials hosting flat bands. As a particular example, we consider time-reversal symmetric pseudospin-1 semimetal, with a pair of three-band crossing points at which a flat band intersects with a Dirac cone, and focus on the s-wave inter-node pairing channel. The nearly dispersionless nature of the flat band promotes local Cooper pair formation so that the system can be considered as an array of superconducting grains. Due to dispersive bands, Andreev scattering between the grains gives rise to the global phase-coherent superconductivity at low temperatures. We develop a theory to calculate transition temperature between the preformed Cooper pair state and the phase-coherent state for different interaction strengths in the Cooper channel.