We will show that the anomalous magnetic moment experimental data of muon and electron $(g-2)_{mu,e}$ can be explained simultaneously in simple extensions of the 3-3-1 models consisting of new heavy neutrinos and a singly charged Higgs boson. The heavy neutrinos generate active neutrinos masses and mixing through the general seesaw mechanism. They also have non-zero Yukawa couplings with singly charged Higgs bosons and right-handed charged leptons, which result in large one-loop contributions known as chirally-enhanced ones. Numerical investigation confirms a conclusion indicated previously that these contributions are the key point to explain the large $(g-2)_{mu, e}$ data, provided that the inverse seesaw mechanism is necessary to allow both conditions that heavy neutrino masses are above few hundred GeV and non-unitary part of the active neutrino mixing matrix must be large enough.