New data for the $^mbox{nat}$V(p,x) reactions have been measured in the range 26-70 MeV, with production of the nuclides $^{47}$Sc, $^{43}$Sc, $^{44m}$Sc, $^{44g}$Sc, $^{46}$Sc, $^{48}$Sc, $^{42}$K, $^{43}$K, $^{48}$V, $^{48}$Cr, $^{49}$Cr, and $^{51}$Cr. The focus is on the production of $^{47}$Sc, a $beta^-$-emitter suitable for innovative radiotheranostic applications in nuclear medicine. The measured cross sections for this radionuclide and its contaminants are compared with the theoretical excitation functions calculated with the TALYS code. In view of novel radiopharmaceutical applications, it is essential to accurately describe these cross-sections for the evaluation of yields, purities, and dose releases. Hence, we optimize the level-density parameters of the microscopic models in the TALYS code to obtain the best possible descriptions of the new data. We consider different irradiation conditions to estimate the production yields from the cross sections determined in this work.
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