We pursue a program to confront observations with arbitrarily inhomogeneous cosmologies beyond the FLRW metric. The main idea is to test the Copernican principle rather than assuming it a priori. We consider the $Lambda$CDM model endowed with a spherical $Lambda$LTB inhomogeneity around us, that is, we assume isotropy and test the hypothesis of homogeneity. We confront the $Lambda$LTB model with the latest available data from CMB, BAO, type Ia supernovae, local $H_0$, cosmic chronometers, Compton y-distortion and kinetic Sunyaev-Zeldovich effect. We find that these data can constrain tightly this extra inhomogeneity, almost to the cosmic variance level: on scales $gtrsim 100$ Mpc structures can have a small non-Copernican effective contrast of just $delta_L sim 0.01$. Furthermore, the constraints on the standard $Lambda$CDM parameters are not weakened after marginalizing over the parameters that model the local structure, to which we assign ignorance priors. In other words, dropping the FLRW metric assumption does not imply worse constraints on the cosmological parameters. This positive result confirms that the present and future data can be meaningfully analyzed within the framework of inhomogeneous cosmology.