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Generative Self-training for Cross-domain Unsupervised Tagged-to-Cine MRI Synthesis

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 Added by Xiaofeng Liu
 Publication date 2021
and research's language is English




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Self-training based unsupervised domain adaptation (UDA) has shown great potential to address the problem of domain shift, when applying a trained deep learning model in a source domain to unlabeled target domains. However, while the self-training UDA has demonstrated its effectiveness on discriminative tasks, such as classification and segmentation, via the reliable pseudo-label selection based on the softmax discrete histogram, the self-training UDA for generative tasks, such as image synthesis, is not fully investigated. In this work, we propose a novel generative self-training (GST) UDA framework with continuous value prediction and regression objective for cross-domain image synthesis. Specifically, we propose to filter the pseudo-label with an uncertainty mask, and quantify the predictive confidence of generated images with practical variational Bayes learning. The fast test-time adaptation is achieved by a round-based alternative optimization scheme. We validated our framework on the tagged-to-cine magnetic resonance imaging (MRI) synthesis problem, where datasets in the source and target domains were acquired from different scanners or centers. Extensive validations were carried out to verify our framework against popular adversarial training UDA methods. Results show that our GST, with tagged MRI of test subjects in new target domains, improved the synthesis quality by a large margin, compared with the adversarial training UDA methods.

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Unsupervised domain adaptation (UDA) aims to transfer the knowledge on a labeled source domain distribution to perform well on an unlabeled target domain. Recently, the deep self-training involves an iterative process of predicting on the target domain and then taking the confident predictions as hard pseudo-labels for retraining. However, the pseudo-labels are usually unreliable, and easily leading to deviated solutions with propagated errors. In this paper, we resort to the energy-based model and constrain the training of the unlabeled target sample with the energy function minimization objective. It can be applied as a simple additional regularization. In this framework, it is possible to gain the benefits of the energy-based model, while retaining strong discriminative performance following a plug-and-play fashion. We deliver extensive experiments on the most popular and large scale UDA benchmarks of image classification as well as semantic segmentation to demonstrate its generality and effectiveness.
199 - Rui Wang , Zuxuan Wu , Zejia Weng 2021
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