This paper is devoted to establishing the optimal decay rate of the global large solution to compressible nematic liquid crystal equations when the initial perturbation is large and belongs to $L^1(mathbb R^3)cap H^2(mathbb R^3)$. More precisely, we show that the first and second order spatial derivatives of large solution $(rho-1, u, abla d)(t)$ converges to zero at the $L^2-$rate $(1+t)^{-frac54}$ and $L^2-$rate $(1+t)^{-frac74}$ respectively, which are optimal in the sense that they coincide with the decay rates of solution to the heat equation. Thus, we establish optimal decay rate for the second order derivative of global large solution studied in [12,18] since the compressible nematic liquid crystal flow becomes the compressible Navier-Stokes equations when the director is a constant vector. It is worth noticing that there is no decay loss for the highest-order spatial derivative of solution although the associated initial perturbation is large. Moreover, we also establish the lower bound of decay rates of $(rho-1, u, abla d)(t)$ itself and its spatial derivative, which coincide with the upper one. Therefore, the decay rates of global large solution $ abla^2(rho-1,u, abla d)(t)$ $(k=0,1,2)$ are actually optimal.
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