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Register a new userRegularization by Adversarial Learning for Ultrasound Elasticity Imaging
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Added by
Narges Mohammadi
Publication date
2021
fields
Electronic Engineering
and research's language is
English
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Classical model-based imaging methods for ultrasound elasticity inverse problem require prior constraints about the underlying elasticity patterns, while finding the appropriate hand-crafted prior for each tissue type is a challenge. In contrast, standard data-driven methods count solely on supervised learning on the training data pairs leading to massive network parameters for unnecessary physical model relearning which might not be consistent with the governing physical models of the imaging system. Fusing the physical forward model and noise statistics with data-adaptive priors leads to a united reconstruction framework that guarantees the learned reconstruction agrees with the physical models while coping with the limited training data. In this paper, we propose a new methodology for estimating the elasticity image by solving a regularized optimization problem which benefits from the physics-based modeling via a data-fidelity term and adversarially learned priors via a regularization term. In this method, the regularizer is trained based on the Wasserstein Generative Adversarial Network (WGAN) objective function which tries to distinguish the distribution of clean and noisy images. Leveraging such an adversarial regularizer for parameterizing the distribution of latent images and using gradient descent (GD) for solving the corresponding regularized optimization task leads to stability and convergence of the reconstruction compared to pixel-wise supervised learning schemes. Our simulation results verify the effectiveness and robustness of the proposed methodology with limited training datasets.
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It is known that changes in the mechanical properties of tissues are associated with the onset and progression of certain diseases. Ultrasound elastography is a technique to characterize tissue stiffness using ultrasound imaging either by measuring tissue strain using quasi-static elastography or natural organ pulsation elastography, or by tracing a propagated shear wave induced by a source or a natural vibration using dynamic elastography. In recent years, deep learning has begun to emerge in ultrasound elastography research. In this review, several common deep learning frameworks in the computer vision community, such as multilayer perceptron, convolutional neural network, and recurrent neural network are described. Then, recent advances in ultrasound elastography using such deep learning techniques are revisited in terms of algorithm development and clinical diagnosis. Finally, the current challenges and future developments of deep learning in ultrasound elastography are prospected.
In this paper, SAR image reconstruction with joint phase error estimation (autofocusing) is formulated as an inverse problem. An optimization model utilising a sparsity-enforcing Cauchy regularizer is proposed, and an alternating minimization framework is used to solve it, in which the desired image and the phase errors are optimized alternatively. For the image reconstruction sub-problem (f-sub-problem), two methods are presented capable of handling the problems complex nature, and we thus present two variants of our SAR image autofocusing algorithm. Firstly, we design a complex version of the forward-backward splitting algorithm (CFBA) to solve the f-sub-problem iteratively. For the second variant, the Wirtinger alternating minimization autofocusing (WAMA) method is presented, in which techniques of Wirtinger calculus are utilized to minimize the complex-valued cost function in the f-sub-problem in a direct fashion. For both methods, the phase error estimation sub-problem is solved by simply expanding and observing its cost function. Moreover, the convergence of both algorithms is discussed in detail. By conducting experiments on both simulated scenes and real SAR images, the proposed method is demonstrated to give impressive autofocusing results compared to other state of the art methods.
Iterative self-consistent parallel imaging reconstruction (SPIRiT) is an effective self-calibrated reconstruction model for parallel magnetic resonance imaging (PMRI). The joint L1 norm of wavelet coefficients and joint total variation (TV) regularization terms are incorporated into the SPIRiT model to improve the reconstruction performance. The simultaneous two-directional low-rankness (STDLR) in k-space data is incorporated into SPIRiT to realize improved reconstruction. Recent methods have exploited the nonlocal self-similarity (NSS) of images by imposing nonlocal low-rankness of similar patches to achieve a superior performance. To fully utilize both the NSS in Magnetic resonance (MR) images and calibration consistency in the k-space domain, we propose a nonlocal low-rank (NLR)-SPIRiT model by incorporating NLR regularization into the SPIRiT model. We apply the weighted nuclear norm (WNN) as a surrogate of the rank and employ the Nash equilibrium (NE) formulation and alternating direction method of multipliers (ADMM) to efficiently solve the NLR-SPIRiT model. The experimental results demonstrate the superior performance of NLR-SPIRiT over the state-of-the-art methods via three objective metrics and visual comparison.
Limitations on bandwidth and power consumption impose strict bounds on data rates of diagnostic imaging systems. Consequently, the design of suitable (i.e. task- and data-aware) compression and reconstruction techniques has attracted considerable attention in recent years. Compressed sensing emerged as a popular framework for sparse signal reconstruction from a small set of compressed measurements. However, typical compressed sensing designs measure a (non)linearly weighted combination of all input signal elements, which poses practical challenges. These designs are also not necessarily task-optimal. In addition, real-time recovery is hampered by the iterative and time-consuming nature of sparse recovery algorithms. Recently, deep learning methods have shown promise for fast recovery from compressed measurements, but the design of adequate and practical sensing strategies remains a challenge. Here, we propose a deep learning solution termed Deep Probabilistic Sub-sampling (DPS), that learns a task-driven sub-sampling pattern, while jointly training a subsequent task model. Once learned, the task-based sub-sampling patterns are fixed and straightforwardly implementable, e.g. by non-uniform analog-to-digital conversion, sparse array design, or slow-time ultrasound pulsing schemes. The effectiveness of our framework is demonstrated in-silico for sparse signal recovery from partial Fourier measurements, and in-vivo for both anatomical image and tissue-motion (Doppler) reconstruction from sub-sampled medical ultrasound imaging data.
Elasticity image, visualizing the quantitative map of tissue stiffness, can be reconstructed by solving an inverse problem. Classical methods for magnetic resonance elastography (MRE) try to solve a regularized optimization problem comprising a deterministic physical model and a prior constraint as data-fidelity term and regularization term, respectively. For improving the elasticity reconstructions, appropriate prior about the underlying elasticity distribution is required which is not unique. This article proposes an infused approach for MRE reconstruction by integrating the statistical representation of the physical laws of harmonic motions and learning-based prior. For data-fidelity term, we use a statistical linear-algebraic model of equilibrium equations and for the regularizer, data-driven regularization by denoising (RED) is utilized. In the proposed optimization paradigm, the regularizer gradient is simply replaced by the residual of learned denoiser leading to time-efficient computation and convex explicit objective function. Simulation results of elasticity reconstruction verify the effectiveness of the proposed approach.
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