We consider the large data scattering problem for the 2D and 3D cubic-quintic NLS in the focusing-focusing regime. Our attention is firstly restricted to the 2D space, where the cubic nonlinearity is $L^2$-critical. We establish a new type of scattering criterion that is uniquely determined by the mass of the initial data, which differs from the classical setting based on the Lyapunov functional. At the end, we also formulate a solely mass-determining scattering threshold for the 3D cubic-quintic NLS in the focusing-focusing regime.