The paper analyses possible transfers of bodies from the main asteroid belt (MBA) to the Centaur region. The orbits of asteroids in the 2:1 mean motion resonance (MMR) with Jupiter are analysed. We selected the asteroids that are in resonant orbits with e > 0.3 whose absolute magnitudes H do not exceed 16m. The total number of the orbits amounts to 152. Numerical calculations were performed to evaluate the evolution of the orbits over 100,000-year time interval with projects for the future. Six bodies are found to have moved from the 2:1 commensurability zone to the Centaur population. The transfer time of these bodies to the Centaur zone ranges from 4,600 to 70,000 yr. Such transfers occur after orbits leave the resonance and the bodies approach Jupiter. Where after reaching sufficient orbital eccentricities bodies approach a terrestrial planet, their orbits go out of the MMR. Accuracy estimations are carried out to confirm the possible asteroid transfers to the Centaur region.