In this paper, we focus on the $(si,t)$-derivation theory of Lie conformal superalgebras. Firstly, we study the fundamental properties of conformal $(si,t)$-derivations. Secondly, we mainly research the interiors of conformal $G$-derivations. Finally, we discuss the relationships between the conformal $(si,t)$-derivations and some generalized conformal derivations of Lie conformal superalgebras.