With the continuous increase of the spectrum and antennas, endogenous sensing is now possible in the fifth generation and future wireless communication systems. However, sensing is a highly complex task for a heterogeneous communication network with massive connections. Seeking multi-domain cooperation is necessary. In this article, we present an integrated sensing and communication (ISAC) system that performs active, passive, and interactive sensing in different stages of communication through hardware and software. We also propose different methods about how multi-user and multi-frequency band cooperate to further enhance the ISAC systems performance. Finally, we elaborate on the advantages of multi-domain cooperation from the physical layer to the network layer for the ISAC system.
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