Image registration as an important basis in signal processing task often encounter the problem of stability and efficiency. Non-learning registration approaches rely on the optimization of the similarity metrics between the fix and moving images. Yet, those approaches are usually costly in both time and space complexity. The problem can be worse when the size of the image is large or the deformations between the images are severe. Recently, deep learning, or precisely saying, the convolutional neural network (CNN) based image registration methods have been widely investigated in the research community and show promising effectiveness to overcome the weakness of non-learning based methods. To explore the advanced learning approaches in image registration problem for solving practical issues, we present in this paper a method of introducing attention mechanism in deformable image registration problem. The proposed approach is based on learning the deformation field with a Transformer framework (AiR) that does not rely on the CNN but can be efficiently trained on GPGPU devices also. In a more vivid interpretation: we treat the image registration problem as the same as a language translation task and introducing a Transformer to tackle the problem. Our method learns an unsupervised generated deformation map and is tested on two benchmark datasets. The source code of the AiR will be released at Gitlab.
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