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Applications of Artificial Intelligence to aid detection of dementia: a narrative review on current capabilities and future directions

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 Added by Renjie Li
 Publication date 2021
and research's language is English




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With populations ageing, the number of people with dementia worldwide is expected to triple to 152 million by 2050. Seventy percent of cases are due to Alzheimers disease (AD) pathology and there is a 10-20 year pre-clinical period before significant cognitive decline occurs. We urgently need, cost effective, objective methods to detect AD, and other dementias, at an early stage. Risk factor modification could prevent 40% of cases and drug trials would have greater chances of success if participants are recruited at an earlier stage. Currently, detection of dementia is largely by pen and paper cognitive tests but these are time consuming and insensitive to pre-clinical phases. Specialist brain scans and body fluid biomarkers can detect the earliest stages of dementia but are too invasive or expensive for widespread use. With the advancement of technology, Artificial Intelligence (AI) shows promising results in assisting with detection of early-stage dementia. Existing AI-aided methods and potential future research directions are reviewed and discussed.

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The increasing need for economic, safe, and sustainable smart manufacturing combined with novel technological enablers, has paved the way for Artificial Intelligence (AI) and Big Data in support of smart manufacturing. This implies a substantial integration of AI, Industrial Internet of Things (IIoT), Robotics, Big data, Blockchain, 5G communications, in support of smart manufacturing and the dynamical processes in modern industries. In this paper, we provide a comprehensive overview of different aspects of AI and Big Data in Industry 4.0 with a particular focus on key applications, techniques, the concepts involved, key enabling technologies, challenges, and research perspective towards deployment of Industry 5.0. In detail, we highlight and analyze how the duo of AI and Big Data is helping in different applications of Industry 4.0. We also highlight key challenges in a successful deployment of AI and Big Data methods in smart industries with a particular emphasis on data-related issues, such as availability, bias, auditing, management, interpretability, communication, and different adversarial attacks and security issues. In a nutshell, we have explored the significance of AI and Big data towards Industry 4.0 applications through panoramic reviews and discussions. We believe, this work will provide a baseline for future research in the domain.
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Antineutrinos are electrically neutral, nearly massless fundamental particles produced in large numbers in the cores of nuclear reactors and in nuclear explosions. In the half century since their discovery, major advances in the understanding of their properties, and in detector technology, have opened the door to a new discipline: Applied Antineutrino Physics. Because antineutrinos are inextricably linked to the process of nuclear fission, many applications of interest are in nuclear nonproliferation. This white paper presents a comprehensive survey of applied antineutrino physics relevant for nonproliferation, summarizes recent advances in the field, describes the overlap of this nascent discipline with other ongoing fundamental and applied antineutrino research, and charts a course for research and development for future applications. It is intended as a resource for policymakers, researchers, and the wider nuclear nonproliferation community.

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