NASAs Spitzer Infrared Spectrometer (IRS) acquired mid-infrared (5-37 microns) disc-averaged spectra of Uranus very near to its equinox in December 2007. A mean spectrum was constructed from observations of multiple central meridian longitudes, spaced equally around the planet, which has provided the opportunity for the most comprehensive globally-averaged characterisation of Uranus temperature and composition ever obtained (Orton et al., 2014 a [arXiv:1407.2120], b [arXiv:1407.2118]). In this work we analyse the disc-averaged spectra at four separate central meridian longitudes to reveal significant longitudinal variability in thermal emission occurring in Uranus stratosphere during the 2007 equinox. We detect a variability of up to 15% at wavelengths sensitive to stratospheric methane, ethane and acetylene at the ~0.1-mbar level. The tropospheric hydrogen-helium continuum and deuterated methane absorption exhibit a negligible variation (less than 2%), constraining the phenomenon to the stratosphere. Building on the forward-modelling analysis of the global average study, we present full optimal estimation
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