We study the $Tbar T$ deformation on a multi-quantum mechanical systems. By introducing the dynamical coordinate transformation, we obtain the deformed theory as well as the solution. We further study the thermo-field-double state under the $Tbar T$ deformation on these systems, including conformal quantum mechanical system, the Sachdev-Ye-Kitaev model, and the model satisfying Eigenstate Thermalization Hypothesis. We find common regenesis phenomena where the signal injected into one local system can regenerate from the other local system. From the bulk picture, we study the deformation on Jackiw-Teitelboim gravity governed by Schwarzian action and find that the regenesis phenomena here are not related to the causal structure of semi-classical wormhole.