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Indoor ventilation is essential for a healthy and comfortable living environment. A key issue is to discharge anthropogenic air contamination such as CO2 gas or, more seriously, airborne respiratory droplets. Here, by employing direct numerical simulations, we study the mechanical displacement ventilation with the realistic range of air changes per hour (ACH) from 1 to 10. For this ventilation scheme, a cool lower zone is established beneath the warm upper zone with the interface height h depending on ACH. For weak ventilation, we find the scalings relation of the interface height h ~ ACH^{3/5}, as suggested by Hunt & Linden (Build. Environ., vol. 34, 1999, pp. 707-720). Also, the CO2 concentration decreases with ACH within this regime. However, for too strong ventilation, the interface height h becomes insensitive to ACH, and the CO2 concentration remains unchanged. Our results are in contrast to the general belief that stronger flow is more helpful to remove contaminants. We work out the physical mechanism governing the transition between the low ACH and the high ACH regimes. It is determined by the relative strength of the kinetic energy from the inflow, potential energy from the stably-stratified layers, and energy loss due to drag. Our findings provide a physics-based guideline to optimize displacement ventilation.
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Understanding ventilation strategy of a supercavity is important for designing high-speed underwater vehicles wherein an artificial gas pocket is created behind a flow separation device for drag reduction. Our study investigates the effect of flow unsteadiness on the ventilation requirements to form (CQf) and collapse (CQc) a supercavity. Imposing flow unsteadiness on the incoming flow has shown an increment in higher CQf at low free stream velocity and lower CQf at high free stream velocity. High-speed imaging reveals distinctly different behaviors in the recirculation region for low and high freestream velocity under unsteady flows. At low free stream velocities, the recirculation region formed downstream of a cavitator shifted vertically with flow unsteadiness, resulting in lower bubble collision and coalescence probability, which is critical for the supercavity formation process. The recirculation region negligibly changed with flow unsteadiness at high free stream velocity and less ventilation is required to form a supercavity compared to that of the steady incoming flow. Such a difference is attributed to the increased transverse Reynolds stress that aids bubble collision in a confined space of the recirculation region. CQc is found to heavily rely on the vertical component of the flow unsteadiness and the free stream velocity. Interfacial instability located upper rear of the supercavity develops noticeably with flow unsteadiness and additional bubbles formed by the distorted interface shed from the supercavity, resulting in an increased CQc. Further analysis on the quantification of such additional bubble leakage rate indicates that the development and amplitude of the interfacial instability accounts for the variation of CQc under a wide range of flow unsteadiness. Our study provides some insights on the design of a ventilation strategy for supercavitating vehicles in practice.
We consider the problem of controlling an invasive mechanical ventilator for pressure-controlled ventilation: a controller must let air in and out of a sedated patients lungs according to a trajectory of airway pressures specified by a clinician. Hand-tuned PID controllers and similar variants have comprised the industry standard for decades, yet can behave poorly by over- or under-shooting their target or oscillating rapidly. We consider a data-driven machine learning approach: First, we train a simulator based on data we collect from an artificial lung. Then, we train deep neural network controllers on these simulators.We show that our controllers are able to track target pressure waveforms significantly better than PID controllers. We further show that a learned controller generalizes across lungs with varying characteristics much more readily than PID controllers do.
To mitigate the SARS-CoV-2 pandemic, officials have employed social distancing and stay-at-home measures, with increased attention to room ventilation emerging only more recently. Effective distancing practices for open spaces can be ineffective for poorly ventilated spaces, both of which are commonly filled with turbulent air. This is typical for indoor spaces that use mixing ventilation. While turbulence initially reduces the risk of infection near a virion-source, it eventually increases the exposure risk for all occupants in a space without ventilation. To complement detailed models aimed at precision, minimalist frameworks are useful to facilitate order of magnitude estimates for how much ventilation provides safety, particularly when circumstances require practical decisions with limited options. Applying basic principles of transport and diffusion, we estimate the time-scale for virions injected into a room of turbulent air to infect an occupant, distinguishing cases of low vs. high initial virion mass loads and virion-destroying vs. virion-reflecting walls. We consider the effect of an open window as a proxy for ventilation. When the airflow is dominated by isotropic turbulence, the minimum area needed to ensure safety depends only on the ratio of total viral load to threshold load for infection. The minimalist estimates here convey simply that the equivalent of ventilation by modest sized open window in classrooms and workplaces significantly improves safety.
Purpose: Functional imaging is emerging as an important tool for lung cancer treatment planning and evaluation. Compared with traditional methods such as nuclear medicine ventilation-perfusion (VQ), positron emission tomography (PET), single photon emission computer tomography (SPECT), or magnetic resonance imaging (MRI), which use contrast agents to form 2D or 3D functional images, ventilation imaging obtained from 4DCT lung images is convenient and cost-effective because of its availability during radiation treatment planning. Current methods of obtaining ventilation images from 4DCT lung images involve deformable image registration (DIR) and a density (HU) change-based algorithm (DIR/HU); therefore the resulting ventilation images are sensitive to the selection of DIR algorithms. Methods: We propose a deep convolutional neural network (CNN)-based method to derive the ventilation images from 4DCT directly without explicit DIR, thereby improving consistency and accuracy of ventilation images. A total of 82 sets of 4DCT and ventilation images from patients with lung cancer were studied using this method. Results: The predicted images were comparable to the label images of the test data. The similarity index and correlation coefficient averaged over the ten-fold cross validation were 0.883+-0.034 and 0.878+-0.028, respectively. Conclusions: The results demonstrate that deep CNN can generate ventilation imaging from 4DCT without explicit deformable image registration, reducing the associated uncertainty.
We present an effective thermal open boundary condition for convective heat transfer problems on domains involving outflow/open boundaries. This boundary condition is energy-stable, and it ensures that the contribution of the open boundary will not cause an ``energy-like temperature functional to increase over time, irrespective of the state of flow on the open boundary. It is effective in coping with thermal open boundaries even in flow regimes where strong vortices or backflows are prevalent on such boundaries, and it is straightforward to implement. Extensive numerical simulations are presented to demonstrate the stability and effectiveness of our method for heat transfer problems with strong vortices and backflows occurring on the open boundaries. Simulation results are compared with previous works to demonstrate the accuracy of the presented method.
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