We generalize the first law of black hole mechanics to the rotating, charged C-metric and to the Ernst metric, both of which have the charged C-metric as a special case. All of these metrics are (3+1)-dimensional, have vanishing cosmological constant, and physically describe a pair of black holes pulled apart to null infinity by some external force. Our first laws are global in the sense of applying to an entire patch of spacetime, as opposed to a neighborhood of the black hole. They are formulated with respect to boost time, whose primacy is motivated by the celestial holographic approach to scattering amplitudes.