Baryon-to-meson and baryon-to-photon transition distribution amplitudes (TDAs) arise in the collinear factorized description of a class of hard exclusive reactions characterized by the exchange of a non-zero baryon number in the cross channel. These TDAs extend the concepts of generalized parton distributions (GPDs) and baryon distribution amplitudes (DAs). In this review we discuss the general properties and physical interpretation of baryon-to-meson and baryon-to-photon TDAs. We argue that these non-perturbative objects are a convenient complementary tool to explore the structure of baryons at the partonic level. We present an overview of hard exclusive reactions admitting a description in terms of TDAs. We discuss the first signals from hard exclusive backward meson electroproduction at JLab with the 6 GeV electron beam and explore further experimental opportunities to access TDAs at JLab@12 GeV, PANDA and J-PARC.