Subscribe to the gold package and get unlimited access to Shamra Academy
Register a new userDenseNet for Breast Tumor Classification in Mammographic Images
297
0
0.0
(
0
)
Ask ChatGPT about the research
No Arabic abstract
Breast cancer is the most common invasive cancer in women, and the second main cause of death. Breast cancer screening is an efficient method to detect indeterminate breast lesions early. The common approaches of screening for women are tomosynthesis and mammography images. However, the traditional manual diagnosis requires an intense workload by pathologists, who are prone to diagnostic errors. Thus, the aim of this study is to build a deep convolutional neural network method for automatic detection, segmentation, and classification of breast lesions in mammography images. Based on deep learning the Mask-CNN (RoIAlign) method was developed to features selection and extraction; and the classification was carried out by DenseNet architecture. Finally, the precision and accuracy of the model is evaluated by cross validation matrix and AUC curve. To summarize, the findings of this study may provide a helpful to improve the diagnosis and efficiency in the automatic tumor localization through the medical image classification.
rate research
Read More
Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional knowledge towards the efficacy of cancer diagnostics. This work investigates a deep learning method combining whole slide images and magnetic resonance images to classify tumors. In particular, our solution comprises a powerful, generic and modular architecture for whole slide image classification. Experiments are prospectively conducted on the 2020 Computational Precision Medicine challenge, in a 3-classes unbalanced classification task. We report cross-validation (resp. validation) balanced-accuracy, kappa and f1 of 0.913, 0.897 and 0.951 (resp. 0.91, 0.90 and 0.94). For research purposes, including reproducibility and direct performance comparisons, our finale submitted models are usable off-the-shelf in a Docker image available at https://hub.docker.com/repository/docker/marvinler/cpm_2020_marvinler.
Automatic breast lesion segmentation in ultrasound helps to diagnose breast cancer, which is one of the dreadful diseases that affect women globally. Segmenting breast regions accurately from ultrasound image is a challenging task due to the inherent speckle artifacts, blurry breast lesion boundaries, and inhomogeneous intensity distributions inside the breast lesion regions. Recently, convolutional neural networks (CNNs) have demonstrated remarkable results in medical image segmentation tasks. However, the convolutional operations in a CNN often focus on local regions, which suffer from limited capabilities in capturing long-range dependencies of the input ultrasound image, resulting in degraded breast lesion segmentation accuracy. In this paper, we develop a deep convolutional neural network equipped with a global guidance block (GGB) and breast lesion boundary detection (BD) modules for boosting the breast ultrasound lesion segmentation. The GGB utilizes the multi-layer integrated feature map as a guidance information to learn the long-range non-local dependencies from both spatial and channel domains. The BD modules learn additional breast lesion boundary map to enhance the boundary quality of a segmentation result refinement. Experimental results on a public dataset and a collected dataset show that our network outperforms other medical image segmentation methods and the recent semantic segmentation methods on breast ultrasound lesion segmentation. Moreover, we also show the application of our network on the ultrasound prostate segmentation, in which our method better identifies prostate regions than state-of-the-art networks.
Ultrasound (US) is one of the most commonly used imaging modalities in both diagnosis and surgical interventions due to its low-cost, safety, and non-invasive characteristic. US image segmentation is currently a unique challenge because of the presence of speckle noise. As manual segmentation requires considerable efforts and time, the development of automatic segmentation algorithms has attracted researchers attention. Although recent methodologies based on convolutional neural networks have shown promising performances, their success relies on the availability of a large number of training data, which is prohibitively difficult for many applications. Therefore, in this study we propose the use of simulated US images and natural images as auxiliary datasets in order to pre-train our segmentation network, and then to fine-tune with limited in vivo data. We show that with as little as 19 in vivo images, fine-tuning the pre-trained network improves the dice score by 21% compared to training from scratch. We also demonstrate that if the same number of natural and simulation US images is available, pre-training on simulation data is preferable.
Classification of malignancy for breast cancer and other cancer types is usually tackled as an object detection problem: Individual lesions are first localized and then classified with respect to malignancy. However, the drawback of this approach is that abstract features incorporating several lesions and areas that are not labelled as a lesion but contain global medically relevant information are thus disregarded: especially for dynamic contrast-enhanced breast MRI, criteria such as background parenchymal enhancement and location within the breast are important for diagnosis and cannot be captured by object detection approaches properly. In this work, we propose a 3D CNN and a multi scale curriculum learning strategy to classify malignancy globally based on an MRI of the whole breast. Thus, the global context of the whole breast rather than individual lesions is taken into account. Our proposed approach does not rely on lesion segmentations, which renders the annotation of training data much more effective than in current object detection approaches. Achieving an AUROC of 0.89, we compare the performance of our approach to Mask R-CNN and Retina U-Net as well as a radiologist. Our performance is on par with approaches that, in contrast to our method, rely on pixelwise segmentations of lesions.
Brain tumor is one of the leading causes of cancer-related death globally among children and adults. Precise classification of brain tumor grade (low-grade and high-grade glioma) at early stage plays a key role in successful prognosis and treatment planning. With recent advances in deep learning, Artificial Intelligence-enabled brain tumor grading systems can assist radiologists in the interpretation of medical images within seconds. The performance of deep learning techniques is, however, highly depended on the size of the annotated dataset. It is extremely challenging to label a large quantity of medical images given the complexity and volume of medical data. In this work, we propose a novel transfer learning based active learning framework to reduce the annotation cost while maintaining stability and robustness of the model performance for brain tumor classification. We employed a 2D slice-based approach to train and finetune our model on the Magnetic Resonance Imaging (MRI) training dataset of 203 patients and a validation dataset of 66 patients which was used as the baseline. With our proposed method, the model achieved Area Under Receiver Operating Characteristic (ROC) Curve (AUC) of 82.89% on a separate test dataset of 66 patients, which was 2.92% higher than the baseline AUC while saving at least 40% of labeling cost. In order to further examine the robustness of our method, we created a balanced dataset, which underwent the same procedure. The model achieved AUC of 82% compared with AUC of 78.48% for the baseline, which reassures the robustness and stability of our proposed transfer learning augmented with active learning framework while significantly reducing the size of training data.
suggested questions
Log in to be able to interact and post comments
comments
Fetching comments
Sign in to be able to follow your search criteria
