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Register a new userMultimodal Gait Recognition for Neurodegenerative Diseases
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Added by
Aite Zhao
Publication date
2021
fields
Informatics Engineering
and research's language is
English
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In recent years, single modality based gait recognition has been extensively explored in the analysis of medical images or other sensory data, and it is recognised that each of the established approaches has different strengths and weaknesses. As an important motor symptom, gait disturbance is usually used for diagnosis and evaluation of diseases; moreover, the use of multi-modality analysis of the patients walking pattern compensates for the one-sidedness of single modality gait recognition methods that only learn gait changes in a single measurement dimension. The fusion of multiple measurement resources has demonstrated promising performance in the identification of gait patterns associated with individual diseases. In this paper, as a useful tool, we propose a novel hybrid model to learn the gait differences between three neurodegenerative diseases, between patients with different severity levels of Parkinsons disease and between healthy individuals and patients, by fusing and aggregating data from multiple sensors. A spatial feature extractor (SFE) is applied to generating representative features of images or signals. In order to capture temporal information from the two modality data, a new correlative memory neural network (CorrMNN) architecture is designed for extracting temporal features. Afterwards, we embed a multi-switch discriminator to associate the observations with individual state estimations. Compared with several state-of-the-art techniques, our proposed framework shows more accurate classification results.
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Over the past decade a wide spectrum of machine learning models have been developed to model the neurodegenerative diseases, associating biomarkers, especially non-intrusive neuroimaging markers, with key clinical scores measuring the cognitive status of patients. Multi-task learning (MTL) has been commonly utilized by these studies to address high dimensionality and small cohort size challenges. However, most existing MTL approaches are based on linear models and suffer from two major limitations: 1) they cannot explicitly consider upper/lower bounds in these clinical scores; 2) they lack the capability to capture complicated non-linear interactions among the variables. In this paper, we propose Subspace Network, an efficient deep modeling approach for non-linear multi-task censored regression. Each layer of the subspace network performs a multi-task censored regression to improve upon the predictions from the last layer via sketching a low-dimensional subspace to perform knowledge transfer among learning tasks. Under mild assumptions, for each layer the parametric subspace can be recovered using only one pass of training data. Empirical results demonstrate that the proposed subspace network quickly picks up the correct parameter subspaces, and outperforms state-of-the-arts in predicting neurodegenerative clinical scores using information in brain imaging.
We introduce Disease Knowledge Transfer (DKT), a novel technique for transferring biomarker information between related neurodegenerative diseases. DKT infers robust multimodal biomarker trajectories in rare neurodegenerative diseases even when only limited, unimodal data is available, by transferring information from larger multimodal datasets from common neurodegenerative diseases. DKT is a joint-disease generative model of biomarker progressions, which exploits biomarker relationships that are shared across diseases. Our proposed method allows, for the first time, the estimation of plausible, multimodal biomarker trajectories in Posterior Cortical Atrophy (PCA), a rare neurodegenerative disease where only unimodal MRI data is available. For this we train DKT on a combined dataset containing subjects with two distinct diseases and sizes of data available: 1) a larger, multimodal typical AD (tAD) dataset from the TADPOLE Challenge, and 2) a smaller unimodal Posterior Cortical Atrophy (PCA) dataset from the Dementia Research Centre (DRC), for which only a limited number of Magnetic Resonance Imaging (MRI) scans are available. Although validation is challenging due to lack of data in PCA, we validate DKT on synthetic data and two patient datasets (TADPOLE and PCA cohorts), showing it can estimate the ground truth parameters in the simulation and predict unseen biomarkers on the two patient datasets. While we demonstrated DKT on Alzheimers variants, we note DKT is generalisable to other forms of related neurodegenerative diseases. Source code for DKT is available online: https://github.com/mrazvan22/dkt.
Gait, the walking pattern of individuals, is one of the important biometrics modalities. Most of the existing gait recognition methods take silhouettes or articulated body models as gait features. These methods suffer from degraded recognition performance when handling confounding variables, such as clothing, carrying and viewing angle. To remedy this issue, we propose a novel AutoEncoder framework, GaitNet, to explicitly disentangle appearance, canonical and pose features from RGB imagery. The LSTM integrates pose features over time as a dynamic gait feature while canonical features are averaged as a static gait feature. Both of them are utilized as classification features. In addition, we collect a Frontal-View Gait (FVG) dataset to focus on gait recognition from frontal-view walking, which is a challenging problem since it contains minimal gait cues compared to other views. FVG also includes other important variations, e.g., walking speed, carrying, and clothing. With extensive experiments on CASIA-B, USF, and FVG datasets, our method demonstrates superior performance to the SOTA quantitatively, the ability of feature disentanglement qualitatively, and promising computational efficiency. We further compare our GaitNet with state-of-the-art face recognition to demonstrate the advantages of gait biometrics identification under certain scenarios, e.g., long distance/lower resolutions, cross viewing angles.
Humans interact in rich and diverse ways with the environment. However, the representation of such behavior by artificial agents is often limited. In this work we present textit{motion concepts}, a novel multimodal representation of human actions in a household environment. A motion concept encompasses a probabilistic description of the kinematics of the action along with its contextual background, namely the location and the objects held during the performance. Furthermore, we present Online Motion Concept Learning (OMCL), a new algorithm which learns novel motion concepts from action demonstrations and recognizes previously learned motion concepts. The algorithm is evaluated on a virtual-reality household environment with the presence of a human avatar. OMCL outperforms standard motion recognition algorithms on an one-shot recognition task, attesting to its potential for sample-efficient recognition of human actions.
One of the major reasons for misclassification of multiplex actions during action recognition is the unavailability of complementary features that provide the semantic information about the actions. In different domains these features are present with different scales and intensities. In existing literature, features are extracted independently in different domains, but the benefits from fusing these multidomain features are not realized. To address this challenge and to extract complete set of complementary information, in this paper, we propose a novel multidomain multimodal fusion framework that extracts complementary and distinct features from different domains of the input modality. We transform input inertial data into signal images, and then make the input modality multidomain and multimodal by transforming spatial domain information into frequency and time-spectrum domain using Discrete Fourier Transform (DFT) and Gabor wavelet transform (GWT) respectively. Features in different domains are extracted by Convolutional Neural networks (CNNs) and then fused by Canonical Correlation based Fusion (CCF) for improving the accuracy of human action recognition. Experimental results on three inertial datasets show the superiority of the proposed method when compared to the state-of-the-art.
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