In quantum mechanics, physical states are represented by rays in Hilbert space $mathscr H$, which is a vector space imbued by an inner product $langle,|,rangle$, whose physical meaning arises as the overlap $langlephi|psirangle$ for $|psirangle$ a pure state (description of preparation) and $langlephi|$ a projective measurement. However, current quantum theory does not formally address the consequences of a changing inner product during the interval between preparation and measurement. We establish a theoretical framework for such a changing inner product, which we show is consistent with standard quantum mechanics. Furthermore, we show that this change is described by a quantum channel, which is tomographically observable, and we elucidate how our result is strongly related to the exploding topic of PT-symmetric quantum mechanics. We explain how to realize experimentally a changing inner product for a qubit in terms of a qutrit protocol with a unitary channel.