We use six different cosmological models to study the recently-released compilation of X-ray and UV flux measurements of 2038 quasars (QSOs) which span the redshift range $0.009 leq z leq 7.5413$. We find, for the full QSO data set, that the parameters of the X-ray and UV luminosities $L_X-L_{UV}$ relation used to standardized these QSOs depend on the cosmological model used to determine these parameters, i.e, it appears that the full QSO data set include QSOs that are not standardized and so cannot be used for the purpose of constraining cosmological parameters. Subsets of the QSO data, restricted to redshifts $z lesssim 1.5-1.7$ obey the $L_X-L_{UV}$ relation in a cosmological-model-independent manner, and so can be used to constrain cosmological parameters. The cosmological constraints from these lower-$z$, smaller QSO data subsets are mostly consistent with, but significantly weaker than, those that follow from baryon acoustic oscillation and Hubble parameter measurements.
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