Artificial neural networks bridge input data into output results by approximately encoding the function that relates them. This is achieved after training the network with a collection of known inputs and results leading to an adjustment of the neuron connections and biases. In the context of quantum detection schemes, neural networks find a natural playground. In particular, in the presence of a target, a quantum sensor delivers a response, i.e., the input data, which can be subsequently processed by a neural network that outputs the target features. We demonstrate that adequately trained neural networks enable to characterize a target with minimal knowledge of the underlying physical model, in regimes where the quantum sensor presents complex responses, and under a significant shot noise due to a reduced number of measurements. We exemplify the method with a development for $^{171}$Yb$^{+}$ atomic sensors. However, our protocol is general, thus applicable to arbitrary quantum detection scenarios.