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Profiling a soft solid layer to passively control the conduit shape in a compliant microchannel during flow

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 Added by Ivan Christov
 Publication date 2020
  fields Physics
and research's language is English




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The shape of a microchannel during flow through it is instrumental to understanding the physics that govern various phenomena ranging from rheological measurements of fluids to separation of particles and cells. Two commonly used approaches for obtaining a desired channel shape (for a given application) are (i) fabricating the microchannel in the requisite shape and (ii) actuating the microchannel walls during flow to obtain the requisite shape. However, these approaches are not always viable. We propose an alternative, passive approach to {it a priori} tune the elastohydrodynamics in a microsystem, towards achieving a pre-determined (but not pre-fabricated) flow geometry when the microchannel is subjected to flow. That is to say, we use the interaction between a soft solid layer, the viscous flow beneath it and the shaped rigid wall above it, to tune the fluid domains shape. Specifically, we study a parallel-wall microchannel whose top wall is a slender soft coating of arbitrary thickness attached to a rigid platform. We derive a nonlinear differential equation for the soft coatings fluid--solid interface, which we use to infer how to achieve specific conduit shapes during flow. Using this theory, we demonstrate the tuning of four categories of microchannel geometries, which establishes, via a proof-of-concept, the viability of our modeling framework. We also explore slip length patterning on the rigid bottom wall of the microchannel, a common technique in microfluidics, as an addition `handle for microchannel shape control. However, we show that this effect is much weaker in practice.



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118 - Ivan C. Christov 2021
Microfluidic devices manufactured from soft polymeric materials have emerged as a paradigm for cheap, disposable and easy-to-prototype fluidic platforms for integrating chemical and biological assays and analyses. The interplay between the flow forces and the inherently compliant conduits of such microfluidic devices requires careful consideration. While mechanical compliance was initially a side-effect of the manufacturing process and materials used, compliance has now become a paradigm, enabling new approaches to microrheological measurements, new modalities of micromixing, and improved sieving of micro- and nano-particles, to name a few applications. This topical review provides an introduction to the physics of these systems. Specifically, the goal of this review is to summarize the recent progress towards a mechanistic understanding of the interaction between non-Newtonian (complex) fluid flows and their deformable confining boundaries. In this context, key experimental results and relevant applications are also explored, hand-in-hand with the fundamental principles for their physics-based modeling. The key topics covered include shear-dependent viscosity of non-Newtonian fluids, hydrodynamic pressure gradients during flow, the elastic response (bulging and deformation) of soft conduits due to flow within, the effect of cross-sectional conduit geometry on the resulting fluid-structure interaction, and key dimensionless groups describing the coupled physics. Open problems and future directions in this nascent field of soft hydraulics, at the intersection of non-Newtonian fluid mechanics, soft matter physics, and microfluidics, are noted.
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