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Register a new userViDi: Descriptive Visual Data Clustering as Radiologist Assistant in COVID-19 Streamline Diagnostic
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In the light of the COVID-19 pandemic, deep learning methods have been widely investigated in detecting COVID-19 from chest X-rays. However, a more pragmatic approach to applying AI methods to a medical diagnosis is designing a framework that facilitates human-machine interaction and expert decision making. Studies have shown that categorization can play an essential rule in accelerating real-world decision making. Inspired by descriptive document clustering, we propose a domain-independent explanatory clustering framework to group contextually related instances and support radiologists decision making. While most descriptive clustering approaches employ domain-specific characteristics to form meaningful clusters, we focus on model-level explanation as a more general-purpose element of every learning process to achieve cluster homogeneity. We employ DeepSHAP to generate homogeneous clusters in terms of disease severity and describe the clusters using favorable and unfavorable saliency maps, which visualize the class discriminating regions of an image. These human-interpretable maps complement radiologist knowledge to investigate the whole cluster at once. Besides, as part of this study, we evaluate a model based on VGG-19, which can identify COVID and pneumonia cases with a positive predictive value of 95% and 97%, respectively, comparable to the recent explainable approaches for COVID diagnosis.
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This paper presents a novel ultrasound imaging point-of-care (PoC) COVID-19 diagnostic system. The adaptive visual diagnostics utilize few-shot learning (FSL) to generate encoded disease state models that are stored and classified using a dictionary of knowns. The novel vocabulary based feature processing of the pipeline adapts the knowledge of a pretrained deep neural network to compress the ultrasound images into discrimative descriptions. The computational efficiency of the FSL approach enables high diagnostic deep learning performance in PoC settings, where training data is limited and the annotation process is not strictly controlled. The algorithm performance is evaluated on the open source COVID-19 POCUS Dataset to validate the systems ability to distinguish COVID-19, pneumonia, and healthy disease states. The results of the empirical analyses demonstrate the appropriate efficiency and accuracy for scalable PoC use. The code for this work will be made publicly available on GitHub upon acceptance.
The Corona Virus (COVID-19) is an internationalpandemic that has quickly propagated throughout the world. The application of deep learning for image classification of chest X-ray images of Covid-19 patients, could become a novel pre-diagnostic detection methodology. However, deep learning architectures require large labelled datasets. This is often a limitation when the subject of research is relatively new as in the case of the virus outbreak, where dealing with small labelled datasets is a challenge. Moreover, in the context of a new highly infectious disease, the datasets are also highly imbalanced,with few observations from positive cases of the new disease. In this work we evaluate the performance of the semi-supervised deep learning architecture known as MixMatch using a very limited number of labelled observations and highly imbalanced labelled dataset. We propose a simple approach for correcting data imbalance, re-weight each observationin the loss function, giving a higher weight to the observationscorresponding to the under-represented class. For unlabelled observations, we propose the usage of the pseudo and augmentedlabels calculated by MixMatch to choose the appropriate weight. The MixMatch method combined with the proposed pseudo-label based balance correction improved classification accuracy by up to 10%, with respect to the non balanced MixMatch algorithm, with statistical significance. We tested our proposed approach with several available datasets using 10, 15 and 20 labelledobservations. Additionally, a new dataset is included among thetested datasets, composed of chest X-ray images of Costa Rican adult patients
The exponential increase in COVID-19 patients is overwhelming healthcare systems across the world. With limited testing kits, it is impossible for every patient with respiratory illness to be tested using conventional techniques (RT-PCR). The tests also have long turn-around time, and limited sensitivity. Detecting possible COVID-19 infections on Chest X-Ray may help quarantine high risk patients while test results are awaited. X-Ray machines are already available in most healthcare systems, and with most modern X-Ray systems already digitized, there is no transportation time involved for the samples either. In this work we propose the use of chest X-Ray to prioritize the selection of patients for further RT-PCR testing. This may be useful in an inpatient setting where the present systems are struggling to decide whether to keep the patient in the ward along with other patients or isolate them in COVID-19 areas. It would also help in identifying patients with high likelihood of COVID with a false negative RT-PCR who would need repeat testing. Further, we propose the use of modern AI techniques to detect the COVID-19 patients using X-Ray images in an automated manner, particularly in settings where radiologists are not available, and help make the proposed testing technology scalable. We present CovidAID: COVID-19 AI Detector, a novel deep neural network based model to triage patients for appropriate testing. On the publicly available covid-chestxray-dataset [2], our model gives 90.5% accuracy with 100% sensitivity (recall) for the COVID-19 infection. We significantly improve upon the results of Covid-Net [10] on the same dataset.
Radiologist examination of chest CT is an effective way for screening COVID-19 cases. In this work, we overcome three challenges in the automation of this process: (i) the limited number of supervised positive cases, (ii) the lack of region-based supervision, and (iii) the variability across acquisition sites. These challenges are met by incorporating a recent augmentation solution called SnapMix, by a new patch embedding technique, and by performing a test-time stability analysis. The three techniques are complementary and are all based on utilizing the heatmaps produced by the Class Activation Mapping (CAM) explainability method. Compared to the current state of the art, we obtain an increase of five percent in the F1 score on a site with a relatively high number of cases, and a gap twice as large for a site with much fewer training images.
The novel corona-virus disease (COVID-19) pandemic has caused a major outbreak in more than 200 countries around the world, leading to a severe impact on the health and life of many people globally. As of mid-July 2020, more than 12 million people were infected, and more than 570,000 death were reported. Computed Tomography (CT) images can be used as an alternative to the time-consuming RT-PCR test, to detect COVID-19. In this work we propose a segmentation framework to detect chest regions in CT images, which are infected by COVID-19. We use an architecture similar to U-Net model, and train it to detect ground glass regions, on pixel level. As the infected regions tend to form a connected component (rather than randomly distributed pixels), we add a suitable regularization term to the loss function, to promote connectivity of the segmentation map for COVID-19 pixels. 2D-anisotropic total-variation is used for this purpose, and therefore the proposed model is called TV-UNet. Through experimental results on a relatively large-scale CT segmentation dataset of around 900 images, we show that adding this new regularization term leads to 2% gain on overall segmentation performance compared to the U-Net model. Our experimental analysis, ranging from visual evaluation of the predicted segmentation results to quantitative assessment of segmentation performance (precision, recall, Dice score, and mIoU) demonstrated great ability to identify COVID-19 associated regions of the lungs, achieving a mIoU rate of over 99%, and a Dice score of around 86%.
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