We prove a number of results to the effect that generic quantum graphs (defined via operator systems as in the work of Duan-Severini-Winter / Weaver) have few symmetries: for a Zariski-dense open set of tuples $(X_1,cdots,X_d)$ of traceless self-adjoint operators in the $ntimes n$ matrix algebra the corresponding operator system has trivial automorphism group, in the largest possible range for the parameters: $2le dle n^2-3$. Moreover, the automorphism group is generically abelian in the larger parameter range $1le dle n^2-2$. This then implies that for those respective parameters the corresponding random-quantum-graph model built on the GUE ensembles of $X_i$s (mimicking the ErdH{o}s-R{e}nyi $G(n,p)$ model) has trivial/abelian automorphism group almost surely.