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A Survey on Modulation Techniques in Molecular Communication via Diffusion

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 Publication date 2020
and research's language is English




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This survey paper focuses on modulation aspects of molecular communication, an emerging field focused on building biologically-inspired systems that embed data within chemical signals. The primary challenges in designing these systems are how to encode and modulate information onto chemical signals, and how to design a receiver that can detect and decode the information from the corrupted chemical signal observed at the destination. In this paper, we focus on modulation design for molecular communication via diffusion systems. In these systems, chemical signals are transported using diffusion, possibly assisted by flow, from the transmitter to the receiver. This tutorial presents recent advancements in modulation and demodulation schemes for molecular communication via diffusion. We compare five different modulation types: concentration-based, type-based, timing-based, spatial, and higher-order modulation techniques. The end-to-end system designs for each modulation scheme are presented. In addition, the key metrics used in the literature to evaluate the performance of these techniques are also presented. Finally, we provide a numerical bit error rate comparison of prominent modulation techniques using analytical models. We close the tutorial with a discussion of key open issues and future research directions for design of molecular communication via diffusion systems.



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Molecular communication is a new field of communication where molecules are used to transfer information. Among the proposed methods, molecular communication via diffusion (MCvD) is particularly effective. One of the main challenges in MCvD is the intersymbol interference (ISI), which inhibits communication at high data rates. Furthermore, at the nano scale, energy efficiency becomes an essential problem. Before addressing these problems, a pre-determined threshold for the received signal must be calculated to make a decision. In this paper, an analytical technique is proposed to determine the optimum threshold, whereas in the literature, these thresholds are generally calculated empirically. Since the main goal of this paper is to build an MCvD system suitable for operating at high data rates without sacrificing quality, new modulation and filtering techniques are proposed to decrease the effects of ISI and enhance energy efficiency. As a transmitter-based solution, a modulation technique for MCvD, molecular transition shift keying (MTSK), is proposed in order to increase the data rate via suppressing the ISI. Furthermore, for energy efficiency, a power adjustment technique that utilizes the residual molecules is proposed. Finally, as a receiver-based solution, a new energy efficient decision feedback filter (DFF) is proposed as a substitute for the decoders such as minimum mean squared error (MMSE) and decision feedback equalizer (DFE). The error performance of DFF and MMSE equalizers are compared in terms of bit error rates, and it is concluded that DFF may be more advantageous when energy efficiency is concerned, due to its lower computational complexity.
Molecular communication between biological entities is a new paradigm in communications. Recently, we studied molecular communication between two nodes formed from synthetic bacteria. Due to high randomness in behavior of bacteria, we used a population of them in each node. The reliability of such communication systems depends on both the maximum concentration of molecules that a transmitter node is able to produce at the receiver node as well as the number of bacteria in each nodes. This maximum concentration of molecules falls with distance which makes the communication to the far nodes nearly impossible. In order to alleviate this problem, in this paper, we propose to use a molecular relaying node. The relay node can resend the message either by the different or the same type of molecules as the original signal from the transmitter. We study two scenarios of relaying. In the first scenario, the relay node simply senses the received concentration and forwards it to the receiver. We show that this sense and forward scenario, depending on the type of molecules used for relaying, results in either increasing the range of concentration of molecules at the receiver or increasing the effective number of bacteria in the receiver node. For both cases of sense and forward relaying, we obtain the resulting improvement in channel capacity. We conclude that multi-type molecular relaying outperforms the single-type relaying. In the second scenario, we study the decode and forward relaying for the M-ary signaling scheme. We show that this relaying strategy increases the reliability of M-ary communication significantly.
Molecular communication via diffusion (MCvD) is a molecular communication method that utilizes the free diffusion of carrier molecules to transfer information at the nano-scale. Due to the random propagation of carrier molecules, inter-symbol interference (ISI) is a major issue in an MCvD system. Alongside ISI, inter-link interference (ILI) is also an issue that increases the total interference for MCvD-based multiple-input-multiple-output (MIMO) approaches. Inspired by the antenna index modulation (IM) concept in traditional communication systems, this paper introduces novel IM-based transmission schemes for MCvD systems. In the paper, molecular space shift keying (MSSK) is proposed as a novel modulation for molecular MIMO systems, and it is found that this method combats ISI and ILI considerably better than existing MIMO approaches. For nano-machines that have access to two different molecules, the direct extension of MSSK, quadrature molecular space shift keying (QMSSK) is also proposed. QMSSK is found to combat ISI considerably well whilst not performing well against ILI-caused errors. In order to combat ILI more effectively, another dual-molecule-based novel modulation scheme called the molecular spatial modulation (MSM) is proposed. Combined with the Gray mapping imposed on the antenna indices, MSM is observed to yield reliable error rates for molecular MIMO systems.
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In this paper, we address the symbol synchronization issue in molecular communication via diffusion (MCvD). Symbol synchronization among chemical sensors and nanomachines is one of the critical challenges to manage complex tasks in the nanonetworks with molecular communication (MC). As in diffusion-based MC, most of the molecules arrive at the receptor closer to the start of the symbol duration, the wrong estimation of the start of the symbol interval leads to a high symbol detection error. By utilizing two types of molecules with different diffusion coefficients we propose a synchronization technique for MCvD. Moreover, we evaluate the symbol-error-rate performance under the proposed symbol synchronization scheme for equal and non-equal symbol duration in MCvD systems.
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