Harmonic oscillators count among the most fundamental quantum systems with important applications in molecular physics, nanoparticle trapping, and quantum information processing. Their equidistant energy level spacing is often a desired feature, but at the same time a challenge if the goal is to deterministically populate specific eigenstates. Here, we show how interference in the transition amplitudes in a bichromatic laser field can suppress the sequential climbing of harmonic oscillator states (Kapitza-Dirac blockade) and achieve selective excitation of energy eigenstates, Schr{o}dinger cats and other non-Gaussian states. This technique can transform the harmonic oscillator into a coherent two-level system or be used to build a large-momentum-transfer beam splitter for matter-waves. To illustrate the universality of the concept, we discuss feasible experiments that cover many orders of magnitude in mass, from single electrons over large molecules to dielectric nanoparticles.
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