Mirage mediation realized in the KKLT flux compactification can naturally suppress the up-type Higgs soft mass at low energy scales, and consequently it can reduce the degree of electroweak fine-tuning up to a loop factor. Interestingly, this feature holds even in high-scale supersymmetry as long as the gauge coupling unification is achieved for light Higgsinos below TeV. Under the experimental constraints on the observed Higgs boson, it turns out that mirage mediation can exhibit low electroweak fine-tuning better than a few percent for stops between about 2 and 6 TeV, i.e., at the same level as in the weak scale supersymmetry, if the Higgsinos are around or below a few hundred GeV.