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Added by
Yuang Shi
Publication date
2020
fields
Informatics Engineering
and research's language is
English
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With the increasing amounts of high-dimensional heterogeneous data to be processed, multi-modality feature selection has become an important research direction in medical image analysis. Traditional methods usually depict the data structure using fixed and predefined similarity matrix for each modality separately, without considering the potential relationship structure across different modalities. In this paper, we propose a novel multi-modality feature selection method, which performs feature selection and local similarity learning simultaniously. Specially, a similarity matrix is learned by jointly considering different imaging modalities. And at the same time, feature selection is conducted by imposing sparse l_{2, 1} norm constraint. The effectiveness of our proposed joint learning method can be well demonstrated by the experimental results on Alzheimers Disease Neuroimaging Initiative (ADNI) dataset, which outperforms existing the state-of-the-art multi-modality approaches.
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We propose to apply a 2D CNN architecture to 3D MRI image Alzheimers disease classification. Training a 3D convolutional neural network (CNN) is time-consuming and computationally expensive. We make use of approximate rank pooling to transform the 3D MRI image volume into a 2D image to use as input to a 2D CNN. We show our proposed CNN model achieves $9.5%$ better Alzheimers disease classification accuracy than the baseline 3D models. We also show that our method allows for efficient training, requiring only 20% of the training time compared to 3D CNN models. The code is available online: https://github.com/UkyVision/alzheimer-project.
Alzheimers Disease (AD) is one of the most concerned neurodegenerative diseases. In the last decade, studies on AD diagnosis attached great significance to artificial intelligence (AI)-based diagnostic algorithms. Among the diverse modality imaging data, T1-weighted MRI and 18F-FDGPET are widely researched for this task. In this paper, we propose a novel convolutional neural network (CNN) to fuse the multi-modality information including T1-MRI and FDG-PDT images around the hippocampal area for the diagnosis of AD. Different from the traditional machine learning algorithms, this method does not require manually extracted features, and utilizes the stateof-art 3D image-processing CNNs to learn features for the diagnosis and prognosis of AD. To validate the performance of the proposed network, we trained the classifier with paired T1-MRI and FDG-PET images using the ADNI datasets, including 731 Normal (NL) subjects, 647 AD subjects, 441 stable MCI (sMCI) subjects and 326 progressive MCI (pMCI) subjects. We obtained the maximal accuracies of 90.10% for NL/AD task, 87.46% for NL/pMCI task, and 76.90% for sMCI/pMCI task. The proposed framework yields comparative results against state-of-the-art approaches. Moreover, the experimental results have demonstrated that (1) segmentation is not a prerequisite by using CNN, (2) the hippocampal area provides enough information to give a reference to AD diagnosis. Keywords: Alzheimers Disease, Multi-modality, Image Classification, CNN, Deep Learning, Hippocampal
In this paper, we investigate the research problem of unsupervised multi-view feature selection. Conventional solutions first simply combine multiple pre-constructed view-specific similarity structures into a collaborative similarity structure, and then perform the subsequent feature selection. These two processes are separate and independent. The collaborative similarity structure remains fixed during feature selection. Further, the simple undirected view combination may adversely reduce the reliability of the ultimate similarity structure for feature selection, as the view-specific similarity structures generally involve noises and outlying entries. To alleviate these problems, we propose an adaptive collaborative similarity learning (ACSL) for multi-view feature selection. We propose to dynamically learn the collaborative similarity structure, and further integrate it with the ultimate feature selection into a unified framework. Moreover, a reasonable rank constraint is devised to adaptively learn an ideal collaborative similarity structure with proper similarity combination weights and desirable neighbor assignment, both of which could positively facilitate the feature selection. An effective solution guaranteed with the proved convergence is derived to iteratively tackle the formulated optimization problem. Experiments demonstrate the superiority of the proposed approach.
Remote sensing (RS) scene classification is a challenging task to predict scene categories of RS images. RS images have two main characters: large intra-class variance caused by large resolution variance and confusing information from large geographic covering area. To ease the negative influence from the above two characters. We propose a Multi-granularity Multi-Level Feature Ensemble Network (MGML-FENet) to efficiently tackle RS scene classification task in this paper. Specifically, we propose Multi-granularity Multi-Level Feature Fusion Branch (MGML-FFB) to extract multi-granularity features in different levels of network by channel-separate feature generator (CS-FG). To avoid the interference from confusing information, we propose Multi-granularity Multi-Level Feature Ensemble Module (MGML-FEM) which can provide diverse predictions by full-channel feature generator (FC-FG). Compared to previous methods, our proposed networks have ability to use structure information and abundant fine-grained features. Furthermore, through ensemble learning method, our proposed MGML-FENets can obtain more convincing final predictions. Extensive classification experiments on multiple RS datasets (AID, NWPU-RESISC45, UC-Merced and VGoogle) demonstrate that our proposed networks achieve better performance than previous state-of-the-art (SOTA) networks. The visualization analysis also shows the good interpretability of MGML-FENet.
Alzheimers disease (AD) is the most prevalent form of dementia. Traditional methods cannot achieve efficient and accurate diagnosis of AD. In this paper, we introduce a novel method based on dynamic functional connectivity (dFC) that can effectively capture changes in the brain. We compare and combine four different types of features including amplitude of low-frequency fluctuation (ALFF), regional homogeneity (ReHo), dFC and the adjacency matrix of different brain structures between subjects. We use graph convolution network (GCN) which consider the similarity of brain structure between patients to solve the classification problem of non-Euclidean domains. The proposed methods accuracy and the area under the receiver operating characteristic curve achieved 91.3% and 98.4%. This result demonstrated that our proposed method can be used for detecting AD.
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