We give the first examples of $mathcal{O}$-acyclic smooth projective geometrically connected varieties over the function field of a complex curve, whose index is not equal to one. More precisely, we construct a family of Enriques surfaces over $mathbb{P}^{1}$ such that any multi-section has even degree over the base $mathbb{P}^{1}$ and show moreover that we can find such a family defined over $mathbb{Q}$. This answers affirmatively a question of Colliot-Thel`ene and Voisin. Furthermore, our construction provides counterexamples to: the failure of the Hasse principle accounted for by the reciprocity obstruction; the integral Hodge conjecture; and universality of Abel-Jacobi maps.