We consider a class of 6D superconformal field theories (SCFTs) which have a large $N$ limit and a semi-classical gravity dual description. Using the quiver-like structure of 6D SCFTs we study a subsector of operators protected from large operator mixing. These operators are characterized by degrees of freedom in a one-dimensional spin chain, and the associated states are generically highly entangled. This provides a concrete realization of qubit-like states in a strongly coupled quantum field theory. Renormalization group flows triggered by deformations of 6D UV fixed points translate to specific deformations of these one-dimensional spin chains. We also present a conjectural spin chain Hamiltonian which tracks the evolution of these states as a function of renormalization group flow, and study qubit manipulation in this setting. Similar considerations hold for theories without $AdS$ duals, such as 6D little string theories and 4D SCFTs obtained from compactification of the partial tensor branch theory on a $T^2$.
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