We present HI observations of the jellyfish galaxy, JO201. This massive galaxy (M$_{ast} = 3.5 times 10^{10}$ M$_odot$) is falling along the line-of-sight towards the centre of a rich cluster (M$_{200} sim 1.6 times 10^{15}$ M$_odot$, $sigma_{cl} sim 982$ km/s) at a high velocity $geq$3363 km/s. Its H$alpha$ emission shows a $sim$40 kpc tail confined closely to its stellar disc and a $sim$100 kpc tail extending further out. We find HI emission coinciding only with the shorter clumpy H$alpha$ tail. In total, we measure an HI mass of M$_{rm HI} = 1.65 times 10^{9}$ M$_odot$, which is about 60% lower than expected based on its stellar mass and stellar surface density. We compared JO201 to another jellyfish in the GASP sample, JO206 (of similar mass but residing in a 10$times$ less massive cluster), and find that they are similarly HI-deficient. Of the total HI mass in JO201, about 30% lies outside the galaxy disc in projection. This HI fraction is probably a lower limit since most of the HI is redshifted relative to the stellar disc and could be outside the disc. The global star formation rate (SFR) analysis of JO201 suggests that its observed SFR would be expected if it had 10$times$ its current HI mass. The disc is the main contributor of the high star formation efficiency at a given HI gas density for both galaxies, but their tails also show higher star formation efficiencies compared to the outer regions of field galaxies. Generally, we find that JO201 and JO206 are similar based on their HI content, stellar mass and star formation rate. This finding is unexpected considering their different environments. A toy model comparing the ram pressure of the ICM versus the restoring forces of these galaxies suggests that the ram pressure strength exerted on them could be comparable if we consider their 3D orbital velocities and radial distances relative to the clusters.