Measurements of The Hubble-Lemaitre constant from early- and local-universe observations show a significant discrepancy. In an attempt to understand the origin of this mismatch, independent techniques to measure H0 are required. One such technique, strong lensing time delays, is set to become a leading contender amongst the myriad methods due to forthcoming large strong lens samples. It is therefore critical to understand the systematic effects inherent in this method. In this paper, we quantify the influence of additional structures along the line-of-sight by adopting realistic light cones derived from the CosmoDC2 semi-analytical extra-galactic catalogue. Using multiple lens plane ray-tracing to create a set of simulated strong lensing systems, we have investigated the impact of line-of-sight structures on time-delay measurements and in turn, on the inferred value of H0. We have also tested the reliability of existing procedures for correcting for line-of-sight effects. We find that if the integrated contribution of the line-of-sight structures is close to a uniform mass sheet, the bias in H0 can be adequately corrected by including a constant external convergence $kappa_{ext}$ in the lens model. However, for realistic line-of-sight structures comprising many galaxies at different redshifts, this simple correction overestimates the bias by an amount that depends linearly on the median external convergence. We, therefore, conclude that lens modelling must incorporate multiple lens planes to account for line-of-sight structures for accurate and precise inference of H0.
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