We show that the $4d$ ${cal N}=1$ $SU(3)$ $N_f=6$ SQCD is the model obtained when compactifying the rank one E-string theory on a three punctured sphere (a trinion) with a particular value of flux. The $SU(6)times SU(6)times U(1)$ global symmetry of the theory, when decomposed into the $SU(2)^3times U(1)^3times SU(6)$ subgroup, corresponds to the three $SU(2)$ symmetries associated to the three punctures and the $U(1)^3 times SU(6)$ subgroup of the $E_8$ symmetry of the E-string theory. All the puncture symmetries are manifest in the UV and thus we can construct ordinary Lagrangians flowing in the IR to any compactification of the E-string theory. We generalize this claim and argue that the ${cal N}=1$ $SU(N+2)$ SQCD in the middle of the conformal window, $N_f=2N+4$, is the theory obtained by compactifying the $6d$ minimal $(D_{N+3},D_{N+3})$ conformal matter SCFT on a sphere with two maximal $SU(N+1)$ punctures, one minimal $SU(2)$ puncture, and with a particular value of flux. The $SU(2N+4)times SU(2N+4)times U(1)$ symmetry of the UV Lagrangian decomposes into $SU(N+1)^2times SU(2)$ puncture symmetries and the $U(1)^3times SU(2N+4)$ subgroup of the $SO(12+4N)$ symmetry group of the $6d$ SCFT. The models constructed from the trinions exhibit a variety of interesting strong coupling effects. For example, one of the dualities arising geometrically from different pair-of-pants decompositions of a four punctured sphere is an $SU(N+2)$ generalization of the Intriligator-Pouliot duality of $SU(2)$ SQCD with $N_f=4$, which is a degenerate, $N=0$, instance of our discussion.
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