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Register a new userCubical Ripser: Software for computing persistent homology of image and volume data
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Added by
Shizuo Kaji
Publication date
2020
fields
Informatics Engineering
and research's language is
English
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We introduce Cubical Ripser for computing persistent homology of image and volume data (more precisely, weighted cubical complexes). To our best knowledge, Cubical Ripser is currently the fastest and the most memory-efficient program for computing persistent homology of weighted cubical complexes. We demonstrate our software with an example of image analysis in which persistent homology and convolutional neural networks are successfully combined. Our open-source implementation is available online.
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We propose a method, based on persistent homology, to uncover topological properties of a priori unknown covariates of neuron activity. Our input data consist of spike train measurements of a set of neurons of interest, a candidate list of the known stimuli that govern neuron activity, and the corresponding state of the animal throughout the experiment performed. Using a generalized linear model for neuron activity and simple assumptions on the effects of the external stimuli, we infer away any contribution to the observed spike trains by the candidate stimuli. Persistent homology then reveals useful information about any further, unknown, covariates.
We develop a method for analyzing spatiotemporal anomalies in geospatial data using topological data analysis (TDA). To do this, we use persistent homology (PH), a tool from TDA that allows one to algorithmically detect geometric voids in a data set and quantify the persistence of these voids. We construct an efficient filtered simplicial complex (FSC) such that the voids in our FSC are in one-to-one correspondence with the anomalies. Our approach goes beyond simply identifying anomalies; it also encodes information about the relationships between anomalies. We use vineyards, which one can interpret as time-varying persistence diagrams (an approach for visualizing PH), to track how the locations of the anomalies change over time. We conduct two case studies using spatially heterogeneous COVID-19 data. First, we examine vaccination rates in New York City by zip code. Second, we study a year-long data set of COVID-19 case rates in neighborhoods in the city of Los Angeles.
We apply modern methods in computational topology to the task of discovering and characterizing phase transitions. As illustrations, we apply our method to four two-dimensional lattice spin models: the Ising, square ice, XY, and fully-frustrated XY models. In particular, we use persistent homology, which computes the births and deaths of individual topological features as a coarse-graining scale or sublevel threshold is increased, to summarize multiscale and high-point correlations in a spin configuration. We employ vector representations of this information called persistence images to formulate and perform the statistical task of distinguishing phases. For the models we consider, a simple logistic regression on these images is sufficient to identify the phase transition. Interpretable order parameters are then read from the weights of the regression. This method suffices to identify magnetization, frustration, and vortex-antivortex structure as relevant features for phase transitions in our models. We also define persistence critical exponents and study how they are related to those critical exponents usually considered.
We propose a general technique for extracting a larger set of stable information from persistent homology computations than is currently done. The persistent homology algorithm is usually viewed as a procedure which starts with a filtered complex and ends with a persistence diagram. This procedure is stable (at least to certain types of perturbations of the input). This justifies the use of the diagram as a signature of the input, and the use of features derived from it in statistics and machine learning. However, these computations also produce other information of great interest to practitioners that is unfortunately unstable. For example, each point in the diagram corresponds to a simplex whose addition in the filtration results in the birth of the corresponding persistent homology class, but this correspondence is unstable. In addition, the persistence diagram is not stable with respect to other procedures that are employed in practice, such as thresholding a point cloud by density. We recast these problems as real-valued functions which are discontinuous but measurable, and then observe that convolving such a function with a suitable function produces a Lipschitz function. The resulting stable function can be estimated by perturbing the input and averaging the output. We illustrate this approach with a number of examples, including a stable localization of a persistent homology generator from brain imaging data.
We present a novel method to explicitly incorporate topological prior knowledge into deep learning based segmentation, which is, to our knowledge, the first work to do so. Our method uses the concept of persistent homology, a tool from topological data analysis, to capture high-level topological characteristics of segmentation results in a way which is differentiable with respect to the pixelwise probability of being assigned to a given class. The topological prior knowledge consists of the sequence of desired Betti numbers of the segmentation. As a proof-of-concept we demonstrate our approach by applying it to the problem of left-ventricle segmentation of cardiac MR images of 500 subjects from the UK Biobank dataset, where we show that it improves segmentation performance in terms of topological correctness without sacrificing pixelwise accuracy.
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