The manipulation of many-body systems often involves time-dependent forces that cause unwanted heating. One strategy to suppress heating is to use time-periodic (Floquet) forces at large driving frequencies. For quantum spin systems with bounded spectra, it was shown rigorously that the heating rate is exponentially small in the driving frequency. Recently, the exponential suppression of heating has also been observed in an experiment with ultracold atoms, realizing a periodically driven Bose-Hubbard model. This model has an unbounded spectrum and, hence, is beyond the reach of previous theoretical approaches. Here, we study this model with two semiclassical approaches valid, respectively, at large and weak interaction strengths. In both limits, we compute the heating rates by studying the statistical probability to encounter a many-body resonance, and obtain a quantitative agreement with the exact diagonalization of the quantum model. Our approach demonstrates the relevance of statistical arguments to Floquet perthermalization of interacting many-body quantum systems.
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