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Deep Learning Techniques for Inverse Problems in Imaging

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 Added by Greg Ongie
 Publication date 2020
and research's language is English




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Recent work in machine learning shows that deep neural networks can be used to solve a wide variety of inverse problems arising in computational imaging. We explore the central prevailing themes of this emerging area and present a taxonomy that can be used to categorize different problems and reconstruction methods. Our taxonomy is organized along two central axes: (1) whether or not a forward model is known and to what extent it is used in training and testing, and (2) whether or not the learning is supervised or unsupervised, i.e., whether or not the training relies on access to matched ground truth image and measurement pairs. We also discuss the trade-offs associated with these different reconstruction approaches, caveats and common failure modes, plus open problems and avenues for future work.



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Recent efforts on solving inverse problems in imaging via deep neural networks use architectures inspired by a fixed number of iterations of an optimization method. The number of iterations is typically quite small due to difficulties in training networks corresponding to more iterations; the resulting solvers cannot be run for more iterations at test time without incurring significant errors. This paper describes an alternative approach corresponding to an infinite number of iterations, yielding a consistent improvement in reconstruction accuracy above state-of-the-art alternatives and where the computational budget can be selected at test time to optimize context-dependent trade-offs between accuracy and computation. The proposed approach leverages ideas from Deep Equilibrium Models, where the fixed-point iteration is constructed to incorporate a known forward model and insights from classical optimization-based reconstruction methods.
Deep neural networks have been applied successfully to a wide variety of inverse problems arising in computational imaging. These networks are typically trained using a forward model that describes the measurement process to be inverted, which is often incorporated directly into the network itself. However, these approaches are sensitive to changes in the forward model: if at test time the forward model varies (even slightly) from the one the network was trained for, the reconstruction performance can degrade substantially. Given a network trained to solve an initial inverse problem with a known forward model, we propose two novel procedures that adapt the network to a change in the forward model, even without full knowledge of the change. Our approaches do not require access to more labeled data (i.e., ground truth images). We show these simple model adaptation approaches achieve empirical success in a variety of inverse problems, including deblurring, super-resolution, and undersampled image reconstruction in magnetic resonance imaging.
The majority of model-based learned image reconstruction methods in medical imaging have been limited to uniform domains, such as pixelated images. If the underlying model is solved on nonuniform meshes, arising from a finite element method typical for nonlinear inverse problems, interpolation and embeddings are needed. To overcome this, we present a flexible framework to extend model-based learning directly to nonuniform meshes, by interpreting the mesh as a graph and formulating our network architectures using graph convolutional neural networks. This gives rise to the proposed iterative Graph Convolutional Newton-type Method (GCNM), which includes the forward model in the solution of the inverse problem, while all updates are directly computed by the network on the problem specific mesh. We present results for Electrical Impedance Tomography, a severely ill-posed nonlinear inverse problem that is frequently solved via optimization-based methods, where the forward problem is solved by finite element methods. Results for absolute EIT imaging are compared to standard iterative methods as well as a graph residual network. We show that the GCNM has strong generalizability to different domain shapes and meshes, out of distribution data as well as experimental data, from purely simulated training data and without transfer training.
Deep Learning (DL), in particular deep neural networks (DNN), by design is purely data-driven and in general does not require physics. This is the strength of DL but also one of its key limitations when applied to science and engineering problems in which underlying physical properties (such as stability, conservation, and positivity) and desired accuracy need to be achieved. DL methods in their original forms are not capable of respecting the underlying mathematical models or achieving desired accuracy even in big-data regimes. On the other hand, many data-driven science and engineering problems, such as inverse problems, typically have limited experimental or observational data, and DL would overfit the data in this case. Leveraging information encoded in the underlying mathematical models, we argue, not only compensates missing information in low data regimes but also provides opportunities to equip DL methods with the underlying physics and hence obtaining higher accuracy. This short communication introduces several model-constrained DL approaches (including both feed-forward DNN and autoencoders) that are capable of learning not only information hidden in the training data but also in the underlying mathematical models to solve inverse problems. We present and provide intuitions for our formulations for general nonlinear problems. For linear inverse problems and linear networks, the first order optimality conditions show that our model-constrained DL approaches can learn information encoded in the underlying mathematical models, and thus can produce consistent or equivalent inverse solutions, while naive purely data-based counterparts cannot.
132 - Miguel del Alamo 2021
We consider ill-posed inverse problems where the forward operator $T$ is unknown, and instead we have access to training data consisting of functions $f_i$ and their noisy images $Tf_i$. This is a practically relevant and challenging problem which current methods are able to solve only under strong assumptions on the training set. Here we propose a new method that requires minimal assumptions on the data, and prove reconstruction rates that depend on the number of training points and the noise level. We show that, in the regime of many training data, the method is minimax optimal. The proposed method employs a type of convolutional neural networks (U-nets) and empirical risk minimization in order to fit the unknown operator. In a nutshell, our approach is based on two ideas: the first is to relate U-nets to multiscale decompositions such as wavelets, thereby linking them to the existing theory, and the second is to use the hierarchical structure of U-nets and the low number of parameters of convolutional neural nets to prove entropy bounds that are practically useful. A significant difference with the existing works on neural networks in nonparametric statistics is that we use them to approximate operators and not functions, which we argue is mathematically more natural and technically more convenient.

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