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Register a new userSource-Relaxed Domain Adaptation for Image Segmentation
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Mathilde Bateson
Publication date
2020
fields
Informatics Engineering
and research's language is
English
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Domain adaptation (DA) has drawn high interests for its capacity to adapt a model trained on labeled source data to perform well on unlabeled or weakly labeled target data from a different domain. Most common DA techniques require the concurrent access to the input images of both the source and target domains. However, in practice, it is common that the source images are not available in the adaptation phase. This is a very frequent DA scenario in medical imaging, for instance, when the source and target images come from different clinical sites. We propose a novel formulation for adapting segmentation networks, which relaxes such a constraint. Our formulation is based on minimizing a label-free entropy loss defined over target-domain data, which we further guide with a domain invariant prior on the segmentation regions. Many priors can be used, derived from anatomical information. Here, a class-ratio prior is learned via an auxiliary network and integrated in the form of a Kullback-Leibler (KL) divergence in our overall loss function. We show the effectiveness of our prior-aware entropy minimization in adapting spine segmentation across different MRI modalities. Our method yields comparable results to several state-of-the-art adaptation techniques, even though is has access to less information, the source images being absent in the adaptation phase. Our straight-forward adaptation strategy only uses one network, contrary to popular adversarial techniques, which cannot perform without the presence of the source images. Our framework can be readily used with various priors and segmentation problems.
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Domain adaptation (DA) has drawn high interest for its capacity to adapt a model trained on labeled source data to perform well on unlabeled or weakly labeled target data from a different domain. Most common DA techniques require concurrent access to the input images of both the source and target domains. However, in practice, privacy concerns often impede the availability of source images in the adaptation phase. This is a very frequent DA scenario in medical imaging, where, for instance, the source and target images could come from different clinical sites. We introduce a source-free domain adaptation for image segmentation. Our formulation is based on minimizing a label-free entropy loss defined over target-domain data, which we further guide with a domain-invariant prior on the segmentation regions. Many priors can be derived from anatomical information. Here, a class ratio prior is estimated from anatomical knowledge and integrated in the form of a Kullback Leibler (KL) divergence in our overall loss function. Furthermore, we motivate our overall loss with an interesting link to maximizing the mutual information between the target images and their label predictions. We show the effectiveness of our prior aware entropy minimization in a variety of domain-adaptation scenarios, with different modalities and applications, including spine, prostate, and cardiac segmentation. Our method yields comparable results to several state of the art adaptation techniques, despite having access to much less information, as the source images are entirely absent in our adaptation phase. Our straightforward adaptation strategy uses only one network, contrary to popular adversarial techniques, which are not applicable to a source-free DA setting. Our framework can be readily used in a breadth of segmentation problems, and our code is publicly available: https://github.com/mathilde-b/SFDA
We propose to adapt segmentation networks with a constrained formulation, which embeds domain-invariant prior knowledge about the segmentation regions. Such knowledge may take the form of simple anatomical information, e.g., structure size or shape, estimated from source samples or known a priori. Our method imposes domain-invariant inequality constraints on the network outputs of unlabeled target samples. It implicitly matches prediction statistics between target and source domains with permitted uncertainty of prior knowledge. We address our constrained problem with a differentiable penalty, fully suited for standard stochastic gradient descent approaches, removing the need for computationally expensive Lagrangian optimization with dual projections. Unlike current two-step adversarial training, our formulation is based on a single loss in a single network, which simplifies adaptation by avoiding extra adversarial steps, while improving convergence and quality of training. The comparison of our approach with state-of-the-art adversarial methods reveals substantially better performance on the challenging task of adapting spine segmentation across different MRI modalities. Our results also show a robustness to imprecision of size priors, approaching the accuracy of a fully supervised model trained directly in a target domain.Our method can be readily used for various constraints and segmentation problems.
Unsupervised Domain Adaptation (UDA) can tackle the challenge that convolutional neural network(CNN)-based approaches for semantic segmentation heavily rely on the pixel-level annotated data, which is labor-intensive. However, existing UDA approaches in this regard inevitably require the full access to source datasets to reduce the gap between the source and target domains during model adaptation, which are impractical in the real scenarios where the source datasets are private, and thus cannot be released along with the well-trained source models. To cope with this issue, we propose a source-free domain adaptation framework for semantic segmentation, namely SFDA, in which only a well-trained source model and an unlabeled target domain dataset are available for adaptation. SFDA not only enables to recover and preserve the source domain knowledge from the source model via knowledge transfer during model adaptation, but also distills valuable information from the target domain for self-supervised learning. The pixel- and patch-level optimization objectives tailored for semantic segmentation are seamlessly integrated in the framework. The extensive experimental results on numerous benchmark datasets highlight the effectiveness of our framework against the existing UDA approaches relying on source data.
We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and cerebrospinal fluid, in addition to tumorous tissue. Regarding our first innovation, we use a domain adaptation framework that combines a novel multispecies biophysical tumor growth model with a generative adversarial model to create realistic looking synthetic multimodal MR images with known segmentation. Regarding our second innovation, we propose an automatic approach to enrich available segmentation data by computing the segmentation for healthy tissues. This segmentation, which is done using diffeomorphic image registration between the BraTS training data and a set of prelabeled atlases, provides more information for training and reduces the class imbalance problem. Our overall approach is not specific to any particular neural network and can be used in conjunction with existing solutions. We demonstrate the performance improvement using a 2D U-Net for the BraTS18 segmentation challenge. Our biophysics based domain adaptation achieves better results, as compared to the existing state-of-the-art GAN model used to create synthetic data for training.
Image dehazing using learning-based methods has achieved state-of-the-art performance in recent years. However, most existing methods train a dehazing model on synthetic hazy images, which are less able to generalize well to real hazy images due to domain shift. To address this issue, we propose a domain adaptation paradigm, which consists of an image translation module and two image dehazing modules. Specifically, we first apply a bidirectional translation network to bridge the gap between the synthetic and real domains by translating images from one domain to another. And then, we use images before and after translation to train the proposed two image dehazing networks with a consistency constraint. In this phase, we incorporate the real hazy image into the dehazing training via exploiting the properties of the clear image (e.g., dark channel prior and image gradient smoothing) to further improve the domain adaptivity. By training image translation and dehazing network in an end-to-end manner, we can obtain better effects of both image translation and dehazing. Experimental results on both synthetic and real-world images demonstrate that our model performs favorably against the state-of-the-art dehazing algorithms.
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