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Register a new userJoint Distribution and Transitions of Pain and Activity in Critically Ill Patients
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Pain and physical function are both essential indices of recovery in critically ill patients in the Intensive Care Units (ICU). Simultaneous monitoring of pain intensity and patient activity can be important for determining which analgesic interventions can optimize mobility and function, while minimizing opioid harm. Nonetheless, so far, our knowledge of the relation between pain and activity has been limited to manual and sporadic activity assessments. In recent years, wearable devices equipped with 3-axis accelerometers have been used in many domains to provide a continuous and automated measure of mobility and physical activity. In this study, we collected activity intensity data from 57 ICU patients, using the Actigraph GT3X device. We also collected relevant clinical information, including nurse assessments of pain intensity, recorded every 1-4 hours. Our results show the joint distribution and state transition of joint activity and pain states in critically ill patients.
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Sleep has been shown to be an indispensable and important component of patients recovery process. Nonetheless, sleep quality of patients in the Intensive Care Unit (ICU) is often low, due to factors such as noise, pain, and frequent nursing care activities. Frequent sleep disruptions by the medical staff and/or visitors at certain times might lead to disruption of patient sleep-wake cycle and can also impact the severity of pain. Examining the association between sleep quality and frequent visitation has been difficult, due to lack of automated methods for visitation detection. In this study, we recruited 38 patients to automatically assess visitation frequency from captured video frames. We used the DensePose R-CNN (ResNet-101) model to calculate the number of people in the room in a video frame. We examined when patients are interrupted the most, and we examined the association between frequent disruptions and patient outcomes on pain and length of stay.
Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the emerging availability of streaming electronic health record data or capture time-sensitive individual physiological patterns, a critical task in the intensive care unit. We propose a novel acuity score framework (DeepSOFA) that leverages temporal measurements and interpretable deep learning models to assess illness severity at any point during an ICU stay. We compare DeepSOFA with SOFA (Sequential Organ Failure Assessment) baseline models using the same model inputs and find that at any point during an ICU admission, DeepSOFA yields significantly more accurate predictions of in-hospital mortality. A DeepSOFA model developed in a public database and validated in a single institutional cohort had a mean AUC for the entire ICU stay of 0.90 (95% CI 0.90-0.91) compared with baseline SOFA models with mean AUC 0.79 (95% CI 0.79-0.80) and 0.85 (95% CI 0.85-0.86). Deep models are well-suited to identify ICU patients in need of life-saving interventions prior to the occurrence of an unexpected adverse event and inform shared decision-making processes among patients, providers, and families regarding goals of care and optimal resource utilization.
Internet of Things (IoT) has triggered a rapid increase in the number of connected devices and new use cases of wireless communications. To meet the new demands, the fifth generation (5G) of wireless communication systems features native machine type communication (MTC) services in addition to traditional human type communication (HTC) services. Some of the main challenges are the heterogeneous requirements and the sporadic traffic of massive MTC (mMTC), which makes the orthogonal allocation of resources infeasible. To overcome this problem, grant free non-orthogonal multiple access schemes have been proposed alongside with sparse signal recovery algorithms. While most of the related works have considered only homogeneous networks, we focus on a scenario where an enhanced mobile broadband (eMBB) device and multiple MTC devices share the same radio resources. We exploit the approximate message passing (AMP) algorithm for joint device activity detection and channel estimation of MTC devices in the presence of interference from eMBB, and evaluate the system performance in terms of receiver operating characteristics (ROC) and channel estimation errors. Moreover, we also propose two new pilot sequence generation strategies which improve the detection capabilities of the MTC receiver without affecting the eMBB service.
Human Activity Recognition (HAR), based on machine and deep learning algorithms is considered one of the most promising technologies to monitor professional and daily life activities for different categories of people (e.g., athletes, elderly, kids, employers) in order to provide a variety of services related, for example to well-being, empowering of technical performances, prevention of risky situation, and educational purposes. However, the analysis of the effectiveness and the efficiency of HAR methodologies suffers from the lack of a standard workflow, which might represent the baseline for the estimation of the quality of the developed pattern recognition models. This makes the comparison among different approaches a challenging task. In addition, researchers can make mistakes that, when not detected, definitely affect the achieved results. To mitigate such issues, this paper proposes an open-source automatic and highly configurable framework, named B-HAR, for the definition, standardization, and development of a baseline framework in order to evaluate and compare HAR methodologies. It implements the most popular data processing methods for data preparation and the most commonly used machine and deep learning pattern recognition models.
In this paper, we propose a turbo receiver for joint activity detection and data decoding in grant-free massive random access, which iterates between a detector and a belief propagation (BP)-based channel decoder. Specifically, responsible for user activity detection, channel estimation, and soft data symbol detection, the detector is developed based on a bilinear inference problem that exploits the common sparsity pattern in the received pilot and data signals. The bilinear generalized approximate message passing (BiG-AMP) algorithm is adopted to solve the problem using probabilities of the transmitted data symbols estimated by the channel decoder as prior knowledge. In addition, extrinsic information is derived from the detector to improve the channel decoding accuracy of the decoder. Simulation results show significant improvements achieved by the proposed turbo receiver compared with conventional designs.
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