We present a novel hyperbolic reformulation of the Serre-Green-Naghdi (SGN) model for the description of dispersive water waves. Contrarily to the classical Boussinesq-type models, it contains only first order derivatives, thus allowing to overcome the numerical difficulties and the severe time step restrictions arising from higher order terms. The proposed model reduces to the original SGN model when an artificial sound speed tends to infinity. Moreover, it is endowed with an energy conservation law from which the energy conservation law associated with the original SGN model is retrieved when the artificial sound speed goes to infinity. The governing partial differential equations are then solved at the aid of high order ADER discontinuous Galerkin finite element schemes. The new model has been successfully validated against numerical and experimental results, for both flat and non-flat bottom. For bottom topographies with large variations, the new model proposed in this paper provides more accurate results with respect to the hyperbolic reformulation of the SGN model with the mild bottom approximation recently proposed in C. Escalante, M. Dumbser and M.J. Castro. An efficient hyperbolic relaxation system for dispersive non-hydrostatic water waves and its solution with high order discontinuous Galerkin schemes, Journal of Computational Physics 2018.