Among some of the current uses of the DC Superconducting QUantum Interference Devices (SQUIDs) are qubit-readouts and sensors for probing properties of quantum materials. We present a rather unique gradiometric niobium SQUID design with state-of-the-art sensitivity in the femto-Tesla range which can be easily tuned to specific readout requirements. The sensor is a next generation of the fractional SQUIDs with tightly optimized input coil and a combination of all measures known for restraining parasitic resonances and other detrimental effects. Our design combines the practical usefulness of well-defined pickup loops for superior imaging kernel and tunable-probing applications with the fractionalization approach to reduce undesired inductances. In addition, our modeling predicts small dimensions for these planar sensors. These features make them of high relevance for material studies and for detection of magnetic fields in small volumes, e.g. as part of a cryogenic scanning quantum imaging apparatus for efficient diagnostics and quantum device readouts. This manuscript will benefit scientists and engineers working on quantum computing technologies by clarifying potential general misconceptions about DC SQUID optimization alongside the introduction of the novel flexible compact DC SQUID design.