Out-of-time-ordered correlation functions (OTOCs) play a crucial role in the study of thermalization, entanglement, and quantum chaos, as they quantify the scrambling of quantum information due to complex interactions. As a consequence of their out-of-time-ordered nature, OTOCs are difficult to measure experimentally. In this Letter we propose an OTOC measurement protocol that does not rely on the reversal of time evolution and is easy to implement in a range of experimental settings. We demonstrate application of our protocol by the characterization of quantum chaos in a periodically driven spin.
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