No Arabic abstract
In many high dimensional classification or regression problems set in a biological context, the complete identification of the set of informative features is often as important as predictive accuracy, since this can provide mechanistic insight and conceptual understanding. Lasso and related algorithms have been widely used since their sparse solutions naturally identify a set of informative features. However, Lasso performs erratically when features are correlated. This limits the use of such algorithms in biological problems, where features such as genes often work together in pathways, leading to sets of highly correlated features. In this paper, we examine the performance of a Lasso derivative, the exclusive group Lasso, in this setting. We propose fast algorithms to solve the exclusive group Lasso, and introduce a solution to the case when the underlying group structure is unknown. The solution combines stability selection with random group allocation and introduction of artificial features. Experiments with both synthetic and real-world data highlight the advantages of this proposed methodology over Lasso in comprehensive selection of informative features.
Genome-wide association studies (GWAS) have achieved great success in the genetic study of Alzheimers disease (AD). Collaborative imaging genetics studies across different research institutions show the effectiveness of detecting genetic risk factors. However, the high dimensionality of GWAS data poses significant challenges in detecting risk SNPs for AD. Selecting relevant features is crucial in predicting the response variable. In this study, we propose a novel Distributed Feature Selection Framework (DFSF) to conduct the large-scale imaging genetics studies across multiple institutions. To speed up the learning process, we propose a family of distributed group Lasso screening rules to identify irrelevant features and remove them from the optimization. Then we select the relevant group features by performing the group Lasso feature selection process in a sequence of parameters. Finally, we employ the stability selection to rank the top risk SNPs that might help detect the early stage of AD. To the best of our knowledge, this is the first distributed feature selection model integrated with group Lasso feature selection as well as detecting the risk genetic factors across multiple research institutions system. Empirical studies are conducted on 809 subjects with 5.9 million SNPs which are distributed across several individual institutions, demonstrating the efficiency and effectiveness of the proposed method.
Using the $ell_1$-norm to regularize the estimation of the parameter vector of a linear model leads to an unstable estimator when covariates are highly correlated. In this paper, we introduce a new penalty function which takes into account the correlation of the design matrix to stabilize the estimation. This norm, called the trace Lasso, uses the trace norm, which is a convex surrogate of the rank, of the selected covariates as the criterion of model complexity. We analyze the properties of our norm, describe an optimization algorithm based on reweighted least-squares, and illustrate the behavior of this norm on synthetic data, showing that it is more adapted to strong correlations than competing methods such as the elastic net.
Privacy preserving in machine learning is a crucial issue in industry informatics since data used for training in industries usually contain sensitive information. Existing differentially private machine learning algorithms have not considered the impact of data correlation, which may lead to more privacy leakage than expected in industrial applications. For example, data collected for traffic monitoring may contain some correlated records due to temporal correlation or user correlation. To fill this gap, we propose a correlation reduction scheme with differentially private feature selection considering the issue of privacy loss when data have correlation in machine learning tasks. %The key to the proposed scheme is to describe the data correlation and select features which leads to less data correlation across the whole dataset. The proposed scheme involves five steps with the goal of managing the extent of data correlation, preserving the privacy, and supporting accuracy in the prediction results. In this way, the impact of data correlation is relieved with the proposed feature selection scheme, and moreover, the privacy issue of data correlation in learning is guaranteed. The proposed method can be widely used in machine learning algorithms which provide services in industrial areas. Experiments show that the proposed scheme can produce better prediction results with machine learning tasks and fewer mean square errors for data queries compared to existing schemes.
Feature selection is a core area of data mining with a recent innovation of graph-driven unsupervised feature selection for linked data. In this setting we have a dataset $mathbf{Y}$ consisting of $n$ instances each with $m$ features and a corresponding $n$ node graph (whose adjacency matrix is $mathbf{A}$) with an edge indicating that the two instances are similar. Existing efforts for unsupervised feature selection on attributed networks have explored either directly regenerating the links by solving for $f$ such that $f(mathbf{y}_i,mathbf{y}_j) approx mathbf{A}_{i,j}$ or finding community structure in $mathbf{A}$ and using the features in $mathbf{Y}$ to predict these communities. However, graph-driven unsupervised feature selection remains an understudied area with respect to exploring more complex guidance. Here we take the novel approach of first building a block model on the graph and then using the block model for feature selection. That is, we discover $mathbf{F}mathbf{M}mathbf{F}^T approx mathbf{A}$ and then find a subset of features $mathcal{S}$ that induces another graph to preserve both $mathbf{F}$ and $mathbf{M}$. We call our approach Block Model Guided Unsupervised Feature Selection (BMGUFS). Experimental results show that our method outperforms the state of the art on several real-world public datasets in finding high-quality features for clustering.
We introduce supervised feature ranking and feature subset selection algorithms for multivariate time series (MTS) classification. Unlike most existing supervised/unsupervised feature selection algorithms for MTS our techniques do not require a feature extraction step to generate a one-dimensional feature vector from the time series. Instead it is based on directly computing similarity between individual time series and assessing how well the resulting cluster structure matches the labels. The techniques are amenable to heterogeneous MTS data, where the time series measurements may have different sampling resolutions, and to multi-modal data.