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Opportunities of a Machine Learning-based Decision Support System for Stroke Rehabilitation Assessment

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 Added by Min Hun Lee
 Publication date 2020
and research's language is English




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Rehabilitation assessment is critical to determine an adequate intervention for a patient. However, the current practices of assessment mainly rely on therapists experience, and assessment is infrequently executed due to the limited availability of a therapist. In this paper, we identified the needs of therapists to assess patients functional abilities (e.g. alternative perspective on assessment with quantitative information on patients exercise motions). As a result, we developed an intelligent decision support system that can identify salient features of assessment using reinforcement learning to assess the quality of motion and summarize patient specific analysis. We evaluated this system with seven therapists using the dataset from 15 patient performing three exercises. The evaluation demonstrates that our system is preferred over a traditional system without analysis while presenting more useful information and significantly increasing the agreement over therapists evaluation from 0.6600 to 0.7108 F1-scores ($p <0.05$). We discuss the importance of presenting contextually relevant and salient information and adaptation to develop a human and machine collaborative decision making system.



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Stroke is the leading cause of serious and long-term disability worldwide. Some studies have shown that motor imagery (MI) based BCI has a positive effect in poststroke rehabilitation. It could help patients promote the reorganization processes in the damaged brain regions. However, offline motor imagery and conventional online motor imagery with feedback (such as rewarding sounds and movements of an avatar) could not reflect the true intention of the patients. In this study, both virtual limbs and functional electrical stimulation (FES) were used as feedback to provide patients a closed-loop sensorimotor integration for motor rehabilitation. The FES system would activate if the user was imagining hand movement of instructed side. Ten stroke patients (7 male, aged 22-70 years, mean 49.5+-15.1) were involved in this study. All of them participated in BCI-FES rehabilitation training for 4 weeks.The average motor imagery accuracies of the ten patients in the last week were 71.3%, which has improved 3% than that in the first week. Five patients Fugl-Meyer Assessment (FMA) scores have been raised. Patient 6, who has have suffered from stroke over two years, achieved the greatest improvement after rehabilitation training (pre FMA: 20, post FMA: 35). In the aspect of brain patterns, the active patterns of the five patients gradually became centralized and shifted to sensorimotor areas (channel C3 and C4) and premotor area (channel FC3 and FC4).In this study, motor imagery based BCI and FES system were combined to provided stoke patients with a closed-loop sensorimotor integration for motor rehabilitation. Result showed evidences that the BCI-FES system is effective in restoring upper extremities motor function in stroke. In future work, more cases are needed to demonstrate its superiority over conventional therapy and explore the potential role of MI in poststroke rehabilitation.
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