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Register a new userLearning Dynamic and Personalized Comorbidity Networks from Event Data using Deep Diffusion Processes
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Comorbid diseases co-occur and progress via complex temporal patterns that vary among individuals. In electronic health records we can observe the different diseases a patient has, but can only infer the temporal relationship between each co-morbid condition. Learning such temporal patterns from event data is crucial for understanding disease pathology and predicting prognoses. To this end, we develop deep diffusion processes (DDP) to model dynamic comorbidity networks, i.e., the temporal relationships between comorbid disease onsets expressed through a dynamic graph. A DDP comprises events modelled as a multi-dimensional point process, with an intensity function parameterized by the edges of a dynamic weighted graph. The graph structure is modulated by a neural network that maps patient history to edge weights, enabling rich temporal representations for disease trajectories. The DDP parameters decouple into clinically meaningful components, which enables serving the dual purpose of accurate risk prediction and intelligible representation of disease pathology. We illustrate these features in experiments using cancer registry data.
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We develop a framework for estimating unknown partial differential equations from noisy data, using a deep learning approach. Given noisy samples of a solution to an unknown PDE, our method interpolates the samples using a neural network, and extracts the PDE by equating derivatives of the neural network approximation. Our method applies to PDEs which are linear combinations of user-defined dictionary functions, and generalizes previous methods that only consider parabolic PDEs. We introduce a regularization scheme that prevents the function approximation from overfitting the data and forces it to be a solution of the underlying PDE. We validate the model on simulated data generated by the known PDEs and added Gaussian noise, and we study our method under different levels of noise. We also compare the error of our method with a Cramer-Rao lower bound for an ordinary differential equation. Our results indicate that our method outperforms other methods in estimating PDEs, especially in the low signal-to-noise regime.
Subjective Logic (SL) is one of well-known belief models that can explicitly deal with uncertain opinions and infer unknown opinions based on a rich set of operators of fusing multiple opinions. Due to high simplicity and applicability, SL has been substantially applied in a variety of decision making in the area of cybersecurity, opinion models, trust models, and/or social network analysis. However, SL and its variants have exposed limitations in predicting uncertain opinions in real-world dynamic network data mainly in three-fold: (1) a lack of scalability to deal with a large-scale network; (2) limited capability to handle heterogeneous topological and temporal dependencies among node-level opinions; and (3) a high sensitivity with conflicting evidence that may generate counterintuitive opinions derived from the evidence. In this work, we proposed a novel deep learning (DL)-based dynamic opinion inference model while node-level opinions are still formalized based on SL meaning that an opinion has a dimension of uncertainty in addition to belief and disbelief in a binomial opinion (i.e., agree or disagree). The proposed DL-based dynamic opinion inference model overcomes the above three limitations by integrating the following techniques: (1) state-of-the-art DL techniques, such as the Graph Convolutional Network (GCN) and the Gated Recurrent Units (GRU) for modeling the topological and temporal heterogeneous dependency information of a given dynamic network; (2) modeling conflicting opinions based on robust statistics; and (3) a highly scalable inference algorithm to predict dynamic, uncertain opinions in a linear computation time. We validated the outperformance of our proposed DL-based algorithm (i.e., GCN-GRU-opinion model) via extensive comparative performance analysis based on four real-world datasets.
Deep neural networks are considered to be state of the art models in many offline machine learning tasks. However, their performance and generalization abilities in online learning tasks are much less understood. Therefore, we focus on online learning and tackle the challenging problem where the underlying process is stationary and ergodic and thus removing the i.i.d. assumption and allowing observations to depend on each other arbitrarily. We prove the generalization abilities of Lipschitz regularized deep neural networks and show that by using those networks, a convergence to the best possible prediction strategy is guaranteed.
In manufacture, steel and other metals are mainly cut and shaped during the fabrication process by computer numerical control (CNC) machines. To keep high productivity and efficiency of the fabrication process, engineers need to monitor the real-time process of CNC machines, and the lifetime management of machine tools. In a real manufacturing process, breakage of machine tools usually happens without any indication, this problem seriously affects the fabrication process for many years. Previous studies suggested many different approaches for monitoring and detecting the breakage of machine tools. However, there still exists a big gap between academic experiments and the complex real fabrication processes such as the high demands of real-time detections, the difficulty in data acquisition and transmission. In this work, we use the spindle current approach to detect the breakage of machine tools, which has the high performance of real-time monitoring, low cost, and easy to install. We analyze the features of the current of a milling machine spindle through tools wearing processes, and then we predict the status of tool breakage by a convolutional neural network(CNN). In addition, we use a BP neural network to understand the reliability of the CNN. The results show that our CNN approach can detect tool breakage with an accuracy of 93%, while the best performance of BP is 80%.
With the widespread use of machine learning for classification, it becomes increasingly important to be able to use weaker kinds of supervision for tasks in which it is hard to obtain standard labeled data. One such kind of supervision is provided pairwise---in the form of Similar (S) pairs (if two examples belong to the same class) and Dissimilar (D) pairs (if two examples belong to different classes). This kind of supervision is realistic in privacy-sensitive domains. Although this problem has been looked at recently, it is unclear how to learn from such supervision under label noise, which is very common when the supervision is crowd-sourced. In this paper, we close this gap and demonstrate how to learn a classifier from noisy S and D labeled data. We perform a detailed investigation of this problem under two realistic noise models and propose two algorithms to learn from noisy S-D data. We also show important connections between learning from such pairwise supervision data and learning from ordinary class-labeled data. Finally, we perform experiments on synthetic and real world datasets and show our noise-informed algorithms outperform noise-blind baselines in learning from noisy pairwise data.
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