We model the ALMA and VLA millimeter radial profiles of the disk around HL Tau to constrain the properties of the dust grains. We adopt the disk evolutionary models of Lynden-Bell & Pringle and calculate their temperature and density structure and emission. These disks are heated by the internal viscosity and irradiated by the central star and a warm envelope. We consider a dust size distribution $n(a) da propto a^{-3.5} da $, and vary the maximum grain size in the atmosphere and the midplane, $a_{rm max}=100 mu$m, 1 mm, and 1cm. We also include dust settling and vary the dust-to-gas mass ratio from 1 to 9 times the ISM value. We find that the models that can fit the observed level of emission along the profiles at all wavelengths have an atmosphere with a maximum grain size $a_{rm max} = 100 mu$m, and a midplane with $a_{rm max}=1$ cm. The disk substructure, with a deficit of emission in the gaps, can be due to dust properties in these regions that are different from those in the rings. We test an opacity effect (different $a_{rm max}$) and a dust mass deficit (smaller dust-to-gas mass ratio) in the gaps. We find that the emission profiles are better reproduced by models with a dust deficit in the gaps, although a combined effect is also possible. These models have a global dust-to-gas mass ratio twice the ISM value, needed to reach the level of emission of the 7.8 mm VLA profile.
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