Entanglement in high energy and and nuclear reactions is receiving great attention. A proper description of these reactions uses density matrices, and the express of entanglement in terms of {it separability}. Quantum tomography bypasses field-theoretic formalism to determine density matrices in terms of experimental observables. We review recent work applying quantum tomography to practical experimental data analysis. We discuss the relation between separability, as defined in quantum information science, and factorization, as defined in high energy physics. When factorization applies, it comes from using separable probes, which tomographically determine separable projections of entangled density matrices.
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