Given a flat-foldable origami crease pattern $G=(V,E)$ (a straight-line drawing of a planar graph on a region of the plane) with a mountain-valley (MV) assignment $mu:Eto{-1,1}$ indicating which creases in $E$ bend convexly (mountain) or concavely (valley), we may emph{flip} a face $F$ of $G$ to create a new MV assignment $mu_F$ which equals $mu$ except for all creases $e$ bordering $F$, where we have $mu_F(e)=-mu(e)$. In this paper we explore the configuration space of face flips for a variety of crease patterns $G$ that are tilings of the plane, proving examples where $mu_F$ results in a MV assignment that is either never, sometimes, or always flat-foldable for various choices of $F$. We also consider the problem of finding, given two foldable MV assignments $mu_1$ and $mu_2$ of a given crease pattern $G$, a minimal sequence of face flips to turn $mu_1$ into $mu_2$. We find polynomial-time algorithms for this in the cases where $G$ is either a square grid or the Miura-ori, and show that this problem is NP-hard in the case where $G$ is the triangle lattice.